node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BP0103 | aspC | BP0103 | BP1185 | Probable class IV aminotransferase; Similar to Staphylococcus aureus D-alanine aminotransferase TR:Q9KWZ6 (EMBL:Y14816) (282 aa) fasta scores: E(): 3.7e-37, 38.849% id in 278 aa, and to Staphylococcus haemolyticus D-alanine aminotransferase Dat SW:DAAA_STAHA (P54694) (282 aa) fasta scores: E(): 1.1e-38, 38.989% id in 277 aa. | Similar to Rhizobium leguminosarum aspartate aminotransferase AspC or AatA SW:AAT_RHILP (O86459) (400 aa) fasta scores: E(): 3.8e-76, 51.76% id in 396 aa, and to Rhizobium meliloti aspartate aminotransferase A AatA or R02325 or smc01578 SW:AATA_RHIME (Q02635) (400 aa) fasta scores: E(): 4.4e-76, 50.75% id in 396 aa. | 0.906 |
BP0103 | hisC | BP0103 | BP3769 | Probable class IV aminotransferase; Similar to Staphylococcus aureus D-alanine aminotransferase TR:Q9KWZ6 (EMBL:Y14816) (282 aa) fasta scores: E(): 3.7e-37, 38.849% id in 278 aa, and to Staphylococcus haemolyticus D-alanine aminotransferase Dat SW:DAAA_STAHA (P54694) (282 aa) fasta scores: E(): 1.1e-38, 38.989% id in 277 aa. | Similar to Escherichia coli histidinol-phosphate aminotransferase HisC SW:HIS8_ECOLI (P06986) (356 aa) fasta scores: E(): 2.3e-20, 31.4% id in 363 aa, and to Neisseria meningitidis histidinol-phosphate aminotransferase NMA1771 TR:Q9JTH8 (EMBL:AL162757) (365 aa) fasta scores: E(): 3.7e-48, 40.84% id in 355 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.920 |
BP0103 | pheA | BP0103 | BP0946 | Probable class IV aminotransferase; Similar to Staphylococcus aureus D-alanine aminotransferase TR:Q9KWZ6 (EMBL:Y14816) (282 aa) fasta scores: E(): 3.7e-37, 38.849% id in 278 aa, and to Staphylococcus haemolyticus D-alanine aminotransferase Dat SW:DAAA_STAHA (P54694) (282 aa) fasta scores: E(): 1.1e-38, 38.989% id in 277 aa. | Similar to Escherichia coli P-protein [includes: chorismate mutase and prephenate dehydratase] PheA or B2599 or Z3891 or Ecs3462 SW:PHEA_ECOLI (P07022) (386 aa) fasta scores: E(): 4.9e-27, 33.773% id in 379 aa, and to Neisseria meningitidis chorismate mutase/prephenate dehydratase nmb0446 TR:Q9K0W1 (EMBL:AE002401) (362 aa) fasta scores: E(): 3.3e-66, 50.276% id in 362 aa. | 0.526 |
aspC | BP0103 | BP1185 | BP0103 | Similar to Rhizobium leguminosarum aspartate aminotransferase AspC or AatA SW:AAT_RHILP (O86459) (400 aa) fasta scores: E(): 3.8e-76, 51.76% id in 396 aa, and to Rhizobium meliloti aspartate aminotransferase A AatA or R02325 or smc01578 SW:AATA_RHIME (Q02635) (400 aa) fasta scores: E(): 4.4e-76, 50.75% id in 396 aa. | Probable class IV aminotransferase; Similar to Staphylococcus aureus D-alanine aminotransferase TR:Q9KWZ6 (EMBL:Y14816) (282 aa) fasta scores: E(): 3.7e-37, 38.849% id in 278 aa, and to Staphylococcus haemolyticus D-alanine aminotransferase Dat SW:DAAA_STAHA (P54694) (282 aa) fasta scores: E(): 1.1e-38, 38.989% id in 277 aa. | 0.906 |
aspC | hisC | BP1185 | BP3769 | Similar to Rhizobium leguminosarum aspartate aminotransferase AspC or AatA SW:AAT_RHILP (O86459) (400 aa) fasta scores: E(): 3.8e-76, 51.76% id in 396 aa, and to Rhizobium meliloti aspartate aminotransferase A AatA or R02325 or smc01578 SW:AATA_RHIME (Q02635) (400 aa) fasta scores: E(): 4.4e-76, 50.75% id in 396 aa. | Similar to Escherichia coli histidinol-phosphate aminotransferase HisC SW:HIS8_ECOLI (P06986) (356 aa) fasta scores: E(): 2.3e-20, 31.4% id in 363 aa, and to Neisseria meningitidis histidinol-phosphate aminotransferase NMA1771 TR:Q9JTH8 (EMBL:AL162757) (365 aa) fasta scores: E(): 3.7e-48, 40.84% id in 355 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.929 |
aspC | pheA | BP1185 | BP0946 | Similar to Rhizobium leguminosarum aspartate aminotransferase AspC or AatA SW:AAT_RHILP (O86459) (400 aa) fasta scores: E(): 3.8e-76, 51.76% id in 396 aa, and to Rhizobium meliloti aspartate aminotransferase A AatA or R02325 or smc01578 SW:AATA_RHIME (Q02635) (400 aa) fasta scores: E(): 4.4e-76, 50.75% id in 396 aa. | Similar to Escherichia coli P-protein [includes: chorismate mutase and prephenate dehydratase] PheA or B2599 or Z3891 or Ecs3462 SW:PHEA_ECOLI (P07022) (386 aa) fasta scores: E(): 4.9e-27, 33.773% id in 379 aa, and to Neisseria meningitidis chorismate mutase/prephenate dehydratase nmb0446 TR:Q9K0W1 (EMBL:AE002401) (362 aa) fasta scores: E(): 3.3e-66, 50.276% id in 362 aa. | 0.984 |
aspC | tyrA | BP1185 | BP0947 | Similar to Rhizobium leguminosarum aspartate aminotransferase AspC or AatA SW:AAT_RHILP (O86459) (400 aa) fasta scores: E(): 3.8e-76, 51.76% id in 396 aa, and to Rhizobium meliloti aspartate aminotransferase A AatA or R02325 or smc01578 SW:AATA_RHIME (Q02635) (400 aa) fasta scores: E(): 4.4e-76, 50.75% id in 396 aa. | Similar to Bordetella bronchiseptica prephenate dehydrogenase TyrA TR:Q9RND8 (EMBL:AF182427) (299 aa) fasta scores: E(): 4.1e-108, 99.331% id in 299 aa, and to Rhizobium meliloti putative cyclohexadienyl dehydrogenase and adh prephenate dehydrogenase protein TR:CAC47240 (EMBL:AL591791) (307 aa) fasta scores: E(): 1.2e-33, 43.110% id in 283 aa. | 0.910 |
hisB | hisC | BP3770 | BP3769 | Imidazoleglycerol-phosphate dehydratase; Similar to C-terminal region of Escherichia coli histidine biosynthesis bifunctional protein hisB [includes: histidinol-phosphatase and imidazoleglycerolphosphate dehydratase] HisB SW:HIS7_ECOLI (P06987) (355 aa) fasta scores: E(): 3.6e-32, 50% id in 194 aa, and to the full length Pseudomonas aeruginosa imidazoleglycerol-phosphate dehydratase PA5143 TR:Q9HU41 (EMBL:AE004927) (197 aa) fasta scores: E(): 1.7e-56, 74.74% id in 194 aa. | Similar to Escherichia coli histidinol-phosphate aminotransferase HisC SW:HIS8_ECOLI (P06986) (356 aa) fasta scores: E(): 2.3e-20, 31.4% id in 363 aa, and to Neisseria meningitidis histidinol-phosphate aminotransferase NMA1771 TR:Q9JTH8 (EMBL:AL162757) (365 aa) fasta scores: E(): 3.7e-48, 40.84% id in 355 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.999 |
hisB | hisD | BP3770 | BP3768 | Imidazoleglycerol-phosphate dehydratase; Similar to C-terminal region of Escherichia coli histidine biosynthesis bifunctional protein hisB [includes: histidinol-phosphatase and imidazoleglycerolphosphate dehydratase] HisB SW:HIS7_ECOLI (P06987) (355 aa) fasta scores: E(): 3.6e-32, 50% id in 194 aa, and to the full length Pseudomonas aeruginosa imidazoleglycerol-phosphate dehydratase PA5143 TR:Q9HU41 (EMBL:AE004927) (197 aa) fasta scores: E(): 1.7e-56, 74.74% id in 194 aa. | Putative histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.999 |
hisB | hisF | BP3770 | BP3773 | Imidazoleglycerol-phosphate dehydratase; Similar to C-terminal region of Escherichia coli histidine biosynthesis bifunctional protein hisB [includes: histidinol-phosphatase and imidazoleglycerolphosphate dehydratase] HisB SW:HIS7_ECOLI (P06987) (355 aa) fasta scores: E(): 3.6e-32, 50% id in 194 aa, and to the full length Pseudomonas aeruginosa imidazoleglycerol-phosphate dehydratase PA5143 TR:Q9HU41 (EMBL:AE004927) (197 aa) fasta scores: E(): 1.7e-56, 74.74% id in 194 aa. | Histidine biosynthesis protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.999 |
hisB | hisG | BP3770 | BP3767 | Imidazoleglycerol-phosphate dehydratase; Similar to C-terminal region of Escherichia coli histidine biosynthesis bifunctional protein hisB [includes: histidinol-phosphatase and imidazoleglycerolphosphate dehydratase] HisB SW:HIS7_ECOLI (P06987) (355 aa) fasta scores: E(): 3.6e-32, 50% id in 194 aa, and to the full length Pseudomonas aeruginosa imidazoleglycerol-phosphate dehydratase PA5143 TR:Q9HU41 (EMBL:AE004927) (197 aa) fasta scores: E(): 1.7e-56, 74.74% id in 194 aa. | Putative ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.997 |
hisB | hisH | BP3770 | BP3771 | Imidazoleglycerol-phosphate dehydratase; Similar to C-terminal region of Escherichia coli histidine biosynthesis bifunctional protein hisB [includes: histidinol-phosphatase and imidazoleglycerolphosphate dehydratase] HisB SW:HIS7_ECOLI (P06987) (355 aa) fasta scores: E(): 3.6e-32, 50% id in 194 aa, and to the full length Pseudomonas aeruginosa imidazoleglycerol-phosphate dehydratase PA5143 TR:Q9HU41 (EMBL:AE004927) (197 aa) fasta scores: E(): 1.7e-56, 74.74% id in 194 aa. | Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.999 |
hisB | hisI | BP3770 | BP3774 | Imidazoleglycerol-phosphate dehydratase; Similar to C-terminal region of Escherichia coli histidine biosynthesis bifunctional protein hisB [includes: histidinol-phosphatase and imidazoleglycerolphosphate dehydratase] HisB SW:HIS7_ECOLI (P06987) (355 aa) fasta scores: E(): 3.6e-32, 50% id in 194 aa, and to the full length Pseudomonas aeruginosa imidazoleglycerol-phosphate dehydratase PA5143 TR:Q9HU41 (EMBL:AE004927) (197 aa) fasta scores: E(): 1.7e-56, 74.74% id in 194 aa. | Putative phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.995 |
hisB | pheA | BP3770 | BP0946 | Imidazoleglycerol-phosphate dehydratase; Similar to C-terminal region of Escherichia coli histidine biosynthesis bifunctional protein hisB [includes: histidinol-phosphatase and imidazoleglycerolphosphate dehydratase] HisB SW:HIS7_ECOLI (P06987) (355 aa) fasta scores: E(): 3.6e-32, 50% id in 194 aa, and to the full length Pseudomonas aeruginosa imidazoleglycerol-phosphate dehydratase PA5143 TR:Q9HU41 (EMBL:AE004927) (197 aa) fasta scores: E(): 1.7e-56, 74.74% id in 194 aa. | Similar to Escherichia coli P-protein [includes: chorismate mutase and prephenate dehydratase] PheA or B2599 or Z3891 or Ecs3462 SW:PHEA_ECOLI (P07022) (386 aa) fasta scores: E(): 4.9e-27, 33.773% id in 379 aa, and to Neisseria meningitidis chorismate mutase/prephenate dehydratase nmb0446 TR:Q9K0W1 (EMBL:AE002401) (362 aa) fasta scores: E(): 3.3e-66, 50.276% id in 362 aa. | 0.607 |
hisC | BP0103 | BP3769 | BP0103 | Similar to Escherichia coli histidinol-phosphate aminotransferase HisC SW:HIS8_ECOLI (P06986) (356 aa) fasta scores: E(): 2.3e-20, 31.4% id in 363 aa, and to Neisseria meningitidis histidinol-phosphate aminotransferase NMA1771 TR:Q9JTH8 (EMBL:AL162757) (365 aa) fasta scores: E(): 3.7e-48, 40.84% id in 355 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Probable class IV aminotransferase; Similar to Staphylococcus aureus D-alanine aminotransferase TR:Q9KWZ6 (EMBL:Y14816) (282 aa) fasta scores: E(): 3.7e-37, 38.849% id in 278 aa, and to Staphylococcus haemolyticus D-alanine aminotransferase Dat SW:DAAA_STAHA (P54694) (282 aa) fasta scores: E(): 1.1e-38, 38.989% id in 277 aa. | 0.920 |
hisC | aspC | BP3769 | BP1185 | Similar to Escherichia coli histidinol-phosphate aminotransferase HisC SW:HIS8_ECOLI (P06986) (356 aa) fasta scores: E(): 2.3e-20, 31.4% id in 363 aa, and to Neisseria meningitidis histidinol-phosphate aminotransferase NMA1771 TR:Q9JTH8 (EMBL:AL162757) (365 aa) fasta scores: E(): 3.7e-48, 40.84% id in 355 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Similar to Rhizobium leguminosarum aspartate aminotransferase AspC or AatA SW:AAT_RHILP (O86459) (400 aa) fasta scores: E(): 3.8e-76, 51.76% id in 396 aa, and to Rhizobium meliloti aspartate aminotransferase A AatA or R02325 or smc01578 SW:AATA_RHIME (Q02635) (400 aa) fasta scores: E(): 4.4e-76, 50.75% id in 396 aa. | 0.929 |
hisC | hisB | BP3769 | BP3770 | Similar to Escherichia coli histidinol-phosphate aminotransferase HisC SW:HIS8_ECOLI (P06986) (356 aa) fasta scores: E(): 2.3e-20, 31.4% id in 363 aa, and to Neisseria meningitidis histidinol-phosphate aminotransferase NMA1771 TR:Q9JTH8 (EMBL:AL162757) (365 aa) fasta scores: E(): 3.7e-48, 40.84% id in 355 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Imidazoleglycerol-phosphate dehydratase; Similar to C-terminal region of Escherichia coli histidine biosynthesis bifunctional protein hisB [includes: histidinol-phosphatase and imidazoleglycerolphosphate dehydratase] HisB SW:HIS7_ECOLI (P06987) (355 aa) fasta scores: E(): 3.6e-32, 50% id in 194 aa, and to the full length Pseudomonas aeruginosa imidazoleglycerol-phosphate dehydratase PA5143 TR:Q9HU41 (EMBL:AE004927) (197 aa) fasta scores: E(): 1.7e-56, 74.74% id in 194 aa. | 0.999 |
hisC | hisD | BP3769 | BP3768 | Similar to Escherichia coli histidinol-phosphate aminotransferase HisC SW:HIS8_ECOLI (P06986) (356 aa) fasta scores: E(): 2.3e-20, 31.4% id in 363 aa, and to Neisseria meningitidis histidinol-phosphate aminotransferase NMA1771 TR:Q9JTH8 (EMBL:AL162757) (365 aa) fasta scores: E(): 3.7e-48, 40.84% id in 355 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Putative histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.997 |
hisC | hisF | BP3769 | BP3773 | Similar to Escherichia coli histidinol-phosphate aminotransferase HisC SW:HIS8_ECOLI (P06986) (356 aa) fasta scores: E(): 2.3e-20, 31.4% id in 363 aa, and to Neisseria meningitidis histidinol-phosphate aminotransferase NMA1771 TR:Q9JTH8 (EMBL:AL162757) (365 aa) fasta scores: E(): 3.7e-48, 40.84% id in 355 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Histidine biosynthesis protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.930 |
hisC | hisG | BP3769 | BP3767 | Similar to Escherichia coli histidinol-phosphate aminotransferase HisC SW:HIS8_ECOLI (P06986) (356 aa) fasta scores: E(): 2.3e-20, 31.4% id in 363 aa, and to Neisseria meningitidis histidinol-phosphate aminotransferase NMA1771 TR:Q9JTH8 (EMBL:AL162757) (365 aa) fasta scores: E(): 3.7e-48, 40.84% id in 355 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Putative ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.947 |