B0177_07515 protein (Streptococcus pseudopneumoniae)

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B0177_07515

Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] (378 aa)

Predicted Functional Partners:

dnaA

0.981

polA

0.963

GCA_001074155_00451

0.953

B0177_04265

0.951

mutS

0.914

B0177_06140

0.905

rnhB

0.903

GCA_001074155_00805

0.900

B0177_01275

0.888

pcrA

0.882

Your Current Organism:

Streptococcus pseudopneumoniae

NCBI taxonomy Id: 257758
Other names: ATCC BAA-960, ATCC:BAA:960, CCUG 49455, CIP 108659, DSM 18670, NCTC 13806, S. pseudopneumoniae, Streptococcus pseudopneumoniae Arbique et al. 2005, strain 0108

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0177_01275	B0177_06140	GCA_001074155_00396	GCA_001074155_00007	Unannotated protein.	Unannotated protein.	0.735
B0177_01275	B0177_07515	GCA_001074155_00396	GCA_001074155_00081	Unannotated protein.	Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]	0.888
B0177_01275	GCA_001074155_00805	GCA_001074155_00396	GCA_001074155_00805	Unannotated protein.	Unannotated protein.	0.760
B0177_01275	polA	GCA_001074155_00396	GCA_001074155_01604	Unannotated protein.	Unannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.684
B0177_04265	B0177_06140	GCA_001074155_00691	GCA_001074155_00007	Unannotated protein.	Unannotated protein.	0.868
B0177_04265	B0177_07515	GCA_001074155_00691	GCA_001074155_00081	Unannotated protein.	Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]	0.951
B0177_04265	polA	GCA_001074155_00691	GCA_001074155_01604	Unannotated protein.	Unannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.867
B0177_04265	rnhB	GCA_001074155_00691	GCA_001074155_00862	Unannotated protein.	Unannotated protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.443
B0177_06140	B0177_01275	GCA_001074155_00007	GCA_001074155_00396	Unannotated protein.	Unannotated protein.	0.735
B0177_06140	B0177_04265	GCA_001074155_00007	GCA_001074155_00691	Unannotated protein.	Unannotated protein.	0.868
B0177_06140	B0177_07515	GCA_001074155_00007	GCA_001074155_00081	Unannotated protein.	Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]	0.905
B0177_06140	GCA_001074155_00805	GCA_001074155_00007	GCA_001074155_00805	Unannotated protein.	Unannotated protein.	0.458
B0177_06140	polA	GCA_001074155_00007	GCA_001074155_01604	Unannotated protein.	Unannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.716
B0177_07515	B0177_01275	GCA_001074155_00081	GCA_001074155_00396	Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]	Unannotated protein.	0.888
B0177_07515	B0177_04265	GCA_001074155_00081	GCA_001074155_00691	Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]	Unannotated protein.	0.951
B0177_07515	B0177_06140	GCA_001074155_00081	GCA_001074155_00007	Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]	Unannotated protein.	0.905
B0177_07515	GCA_001074155_00451	GCA_001074155_00081	GCA_001074155_00451	Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]	Unannotated protein.	0.953
B0177_07515	GCA_001074155_00805	GCA_001074155_00081	GCA_001074155_00805	Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]	Unannotated protein.	0.900
B0177_07515	dnaA	GCA_001074155_00081	GCA_001074155_00080	Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]	Unannotated protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.	0.981
B0177_07515	mutS	GCA_001074155_00081	GCA_001074155_00444	Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]	Unannotated protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.	0.914

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