node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psyc_1249 | argA | Psyc_1249 | Psyc_2089 | L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | 0.455 |
Psyc_1249 | gltB | Psyc_1249 | Psyc_1874 | L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glutamate synthase (NADPH) large subunit; This orf aligns best with NADPH-dependent glutamate synthase proteins as opposed to proteins that use other cofactors. | 0.935 |
Psyc_1249 | pheA | Psyc_1249 | Psyc_1186 | L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Prephenate dehydratase; Contains 3 domains: chorismate mutase, prephenate dehydratase, and an ACT (amino acid synthesis regulatory domain). This enzyme is bifunctional in the phenylalanine synthesis pathway. | 0.612 |
Psyc_1249 | proA | Psyc_1249 | Psyc_0293 | L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.942 |
Psyc_1249 | proB | Psyc_1249 | Psyc_1503 | L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.946 |
Psyc_1249 | proC | Psyc_1249 | Psyc_0165 | L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.955 |
Psyc_1249 | ribB | Psyc_1249 | Psyc_0093 | L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.483 |
argA | Psyc_1249 | Psyc_2089 | Psyc_1249 | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.455 |
argA | argC | Psyc_2089 | Psyc_1501 | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.980 |
argA | gltB | Psyc_2089 | Psyc_1874 | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | Glutamate synthase (NADPH) large subunit; This orf aligns best with NADPH-dependent glutamate synthase proteins as opposed to proteins that use other cofactors. | 0.667 |
argA | pheA | Psyc_2089 | Psyc_1186 | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | Prephenate dehydratase; Contains 3 domains: chorismate mutase, prephenate dehydratase, and an ACT (amino acid synthesis regulatory domain). This enzyme is bifunctional in the phenylalanine synthesis pathway. | 0.493 |
argA | proA | Psyc_2089 | Psyc_0293 | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.420 |
argA | proB | Psyc_2089 | Psyc_1503 | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.539 |
argA | proC | Psyc_2089 | Psyc_0165 | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.532 |
argC | argA | Psyc_1501 | Psyc_2089 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | 0.980 |
argC | gltB | Psyc_1501 | Psyc_1874 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Glutamate synthase (NADPH) large subunit; This orf aligns best with NADPH-dependent glutamate synthase proteins as opposed to proteins that use other cofactors. | 0.609 |
argC | hemE | Psyc_1501 | Psyc_1502 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Putative uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.588 |
argC | pheA | Psyc_1501 | Psyc_1186 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Prephenate dehydratase; Contains 3 domains: chorismate mutase, prephenate dehydratase, and an ACT (amino acid synthesis regulatory domain). This enzyme is bifunctional in the phenylalanine synthesis pathway. | 0.620 |
argC | proB | Psyc_1501 | Psyc_1503 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.570 |
argC | ribB | Psyc_1501 | Psyc_0093 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.461 |