STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccaCCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (446 aa)    
Predicted Functional Partners:
moeB
Molybdopterin biosynthesis protein; Evidence code ER2.
  
 
 0.827
nac
Nascent polypeptide-associated complex, chaperone protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.737
endA
tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity).
 
   
 0.721
Mbur_0948
KH type RNA-binding protein; Evidence code ER3.
  
     0.677
Mbur_2153
UPF0200-family protein; Evidence code ER4.
 
     0.663
rpl26e
LSU ribosomal protein L26e; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
     0.661
Mbur_0903
DUF655 containing protein; Evidence code ER4.
 
   
 0.634
dnaG
Toprim domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
   
 0.633
nusA
Transcription termination factor NusA; Participates in transcription termination. Belongs to the NusA family.
 
     0.598
Mbur_2047
Protein of unknown function with DUF650 and DUF651 domains; Involved in DNA damage repair; Belongs to the Nre family.
  
     0.564
Your Current Organism:
Methanococcoides burtonii
NCBI taxonomy Id: 259564
Other names: M. burtonii DSM 6242, Methanococcoides burtonii DSM 6242, Methanococcoides burtonii str. DSM 6242
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.