node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mbur_1928 | hpt | Mbur_1928 | Mbur_1435 | Bifunctional purine biosynthesis protein purH; Evidence code ER2; AICAR transformylase; Inosinicase; IMP synthetase; ATIC; phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.977 |
Mbur_1928 | purA | Mbur_1928 | Mbur_0119 | Bifunctional purine biosynthesis protein purH; Evidence code ER2; AICAR transformylase; Inosinicase; IMP synthetase; ATIC; phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.987 |
Mbur_1928 | purB | Mbur_1928 | Mbur_1160 | Bifunctional purine biosynthesis protein purH; Evidence code ER2; AICAR transformylase; Inosinicase; IMP synthetase; ATIC; phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | Adenylosuccinate lyase; Evidence code ER2; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.998 |
Mbur_1928 | purC | Mbur_1928 | Mbur_2042 | Bifunctional purine biosynthesis protein purH; Evidence code ER2; AICAR transformylase; Inosinicase; IMP synthetase; ATIC; phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Evidence code ER2; SAICAR synthetase. | 0.990 |
Mbur_1928 | purD | Mbur_1928 | Mbur_1056 | Bifunctional purine biosynthesis protein purH; Evidence code ER2; AICAR transformylase; Inosinicase; IMP synthetase; ATIC; phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | Phosphoribosylamine--glycine ligase; Evidence code ER2; GARS. | 0.990 |
Mbur_1928 | purE | Mbur_1928 | Mbur_0877 | Bifunctional purine biosynthesis protein purH; Evidence code ER2; AICAR transformylase; Inosinicase; IMP synthetase; ATIC; phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.989 |
Mbur_1928 | purF | Mbur_1928 | Mbur_2179 | Bifunctional purine biosynthesis protein purH; Evidence code ER2; AICAR transformylase; Inosinicase; IMP synthetase; ATIC; phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.992 |
Mbur_1928 | purL | Mbur_1928 | Mbur_2051 | Bifunctional purine biosynthesis protein purH; Evidence code ER2; AICAR transformylase; Inosinicase; IMP synthetase; ATIC; phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.984 |
Mbur_1928 | purN | Mbur_1928 | Mbur_1812 | Bifunctional purine biosynthesis protein purH; Evidence code ER2; AICAR transformylase; Inosinicase; IMP synthetase; ATIC; phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | Phosphoribosylglycinamide formyltransferase; Evidence code ER2. | 0.999 |
Mbur_1928 | purQ | Mbur_1928 | Mbur_0461 | Bifunctional purine biosynthesis protein purH; Evidence code ER2; AICAR transformylase; Inosinicase; IMP synthetase; ATIC; phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.984 |
hpt | Mbur_1928 | Mbur_1435 | Mbur_1928 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Bifunctional purine biosynthesis protein purH; Evidence code ER2; AICAR transformylase; Inosinicase; IMP synthetase; ATIC; phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | 0.977 |
hpt | purA | Mbur_1435 | Mbur_0119 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.736 |
hpt | purB | Mbur_1435 | Mbur_1160 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Adenylosuccinate lyase; Evidence code ER2; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.977 |
hpt | purC | Mbur_1435 | Mbur_2042 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Evidence code ER2; SAICAR synthetase. | 0.629 |
hpt | purD | Mbur_1435 | Mbur_1056 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Phosphoribosylamine--glycine ligase; Evidence code ER2; GARS. | 0.610 |
hpt | purE | Mbur_1435 | Mbur_0877 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.714 |
hpt | purF | Mbur_1435 | Mbur_2179 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.690 |
hpt | purL | Mbur_1435 | Mbur_2051 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.581 |
hpt | purN | Mbur_1435 | Mbur_1812 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Phosphoribosylglycinamide formyltransferase; Evidence code ER2. | 0.601 |
hpt | purQ | Mbur_1435 | Mbur_0461 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.585 |