STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mbur_1935Adenylyl cyclase-family protein; Evidence code ER4. (171 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
  0.901
Mbur_0469
Pyruvate kinase; Evidence code ER2; Belongs to the pyruvate kinase family.
    
 0.900
Mbur_2125
Anaerobic ribonucleoside-triphosphate reductase; Evidence code ER3.
     
  0.900
Mbur_2140
Anaerobic ribonucleoside-triphosphate reductase; Evidence code ER3.
     
  0.900
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
    
  0.813
Mbur_1932
3-hydroxy-3-methylglutaryl-CoA synthase; Evidence code ER3; Belongs to the thiolase-like superfamily. UPF0219 family.
     
 0.806
Mbur_1933
Acetoacetyl-CoA thiolase; Evidence code ER3.
       0.806
Mbur_1934
DUF35-domain protein; Evidence code ER4.
       0.806
mptA
GTP cyclohydrolase MptA; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
    
  0.801
Mbur_0301
Radical SAM family protein; Evidence code ER4.
    
  0.801
Your Current Organism:
Methanococcoides burtonii
NCBI taxonomy Id: 259564
Other names: M. burtonii DSM 6242, Methanococcoides burtonii DSM 6242, Methanococcoides burtonii str. DSM 6242
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