STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nirA-2NirA_2; Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors. (555 aa)    
Predicted Functional Partners:
cysH-2
CysH_2; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
 0.999
cysH
CysH_1; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
 0.996
fdhF
FdhF; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
 0.981
cysN
CysN; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
 
  
 0.981
cysK
CysK; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.954
metB
MetB.
  
 0.953
MAP_0390c
Hypothetical protein.
  
 
 0.941
metZ
MetZ; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.939
cysG2
CysG2.
 
  
 0.929
cysA3
CysA3.
 
  
 0.922
Your Current Organism:
Mycobacterium avium
NCBI taxonomy Id: 262316
Other names: M. avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K10, Mycobacterium avium subsp. paratuberculosis str. K-10, Mycobacterium avium subsp. paratuberculosis strain K-10
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.