STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sahHSahH; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (496 aa)    
Predicted Functional Partners:
metH
MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.968
metE
MetE; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.957
cysM2
CysM2.
 
 0.948
metB
MetB.
  
 0.931
metZ
MetZ; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.931
metC
MetC.
    
 0.915
MAP_2279
Hypothetical protein.
     
 0.904
MAP_2055
Hypothetical protein.
     
  0.900
MAP_0390c
Hypothetical protein.
  
 0.864
cysK
CysK; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.864
Your Current Organism:
Mycobacterium avium
NCBI taxonomy Id: 262316
Other names: M. avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K10, Mycobacterium avium subsp. paratuberculosis str. K-10, Mycobacterium avium subsp. paratuberculosis strain K-10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.