STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (387 aa)    
Predicted Functional Partners:
pta
Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
 
 
 0.999
acs
Acs; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.986
aceA
AceA.
   
  
 0.969
MAP_3255
Hypothetical protein; Belongs to the TPP enzyme family.
    
 0.955
aldA
AldA_1; Belongs to the aldehyde dehydrogenase family.
  
 
 0.930
aldA-2
AldA_2; Belongs to the aldehyde dehydrogenase family.
  
 
 0.925
MAP_1658
Hypothetical protein; Belongs to the aldehyde dehydrogenase family.
  
 
 0.925
MAP_2084
Hypothetical protein; Belongs to the aldehyde dehydrogenase family.
  
 
 0.925
MAP_2338
Hypothetical protein; Belongs to the aldehyde dehydrogenase family.
  
 
 0.925
MAP_2583c
Hypothetical protein; Belongs to the aldehyde dehydrogenase family.
  
 
 0.925
Your Current Organism:
Mycobacterium avium
NCBI taxonomy Id: 262316
Other names: M. avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K10, Mycobacterium avium subsp. paratuberculosis str. K-10, Mycobacterium avium subsp. paratuberculosis strain K-10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.