STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabHFabH; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (335 aa)    
Predicted Functional Partners:
fabD
FabD.
 
  
 0.988
fas
Fas.
  
  
 0.980
accD3
AccD3.
 
  
 0.976
kasB
KasB_1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.972
kasA
KasA; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.969
kasB-2
KasB_2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.938
inhA
InhA.
 
  
 0.902
fabG1
FabG1.
 
  
 0.810
acpM
AcpM; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
 
  
 0.804
menA
MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
       0.753
Your Current Organism:
Mycobacterium avium
NCBI taxonomy Id: 262316
Other names: M. avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K10, Mycobacterium avium subsp. paratuberculosis str. K-10, Mycobacterium avium subsp. paratuberculosis strain K-10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.