node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Exig_0181 | Exig_0183 | Exig_0181 | Exig_0183 | PFAM: amino acid permease-associated region; KEGG: gtn:GTNG_3167 probable amino acid permease. | PFAM: regulatory protein TetR; KEGG: gtn:GTNG_3165 transcriptional regulator TetR family. | 0.543 |
Exig_0181 | Exig_0184 | Exig_0181 | Exig_0184 | PFAM: amino acid permease-associated region; KEGG: gtn:GTNG_3167 probable amino acid permease. | KEGG: par:Psyc_2123 hypothetical protein. | 0.448 |
Exig_0181 | kynA | Exig_0181 | Exig_0180 | PFAM: amino acid permease-associated region; KEGG: gtn:GTNG_3167 probable amino acid permease. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.727 |
Exig_0181 | kynB | Exig_0181 | Exig_0179 | PFAM: amino acid permease-associated region; KEGG: gtn:GTNG_3167 probable amino acid permease. | Arylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.721 |
Exig_0181 | kynU | Exig_0181 | Exig_0182 | PFAM: amino acid permease-associated region; KEGG: gtn:GTNG_3167 probable amino acid permease. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.797 |
Exig_0183 | Exig_0181 | Exig_0183 | Exig_0181 | PFAM: regulatory protein TetR; KEGG: gtn:GTNG_3165 transcriptional regulator TetR family. | PFAM: amino acid permease-associated region; KEGG: gtn:GTNG_3167 probable amino acid permease. | 0.543 |
Exig_0183 | Exig_0184 | Exig_0183 | Exig_0184 | PFAM: regulatory protein TetR; KEGG: gtn:GTNG_3165 transcriptional regulator TetR family. | KEGG: par:Psyc_2123 hypothetical protein. | 0.629 |
Exig_0183 | kynA | Exig_0183 | Exig_0180 | PFAM: regulatory protein TetR; KEGG: gtn:GTNG_3165 transcriptional regulator TetR family. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.510 |
Exig_0183 | kynB | Exig_0183 | Exig_0179 | PFAM: regulatory protein TetR; KEGG: gtn:GTNG_3165 transcriptional regulator TetR family. | Arylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.569 |
Exig_0183 | kynU | Exig_0183 | Exig_0182 | PFAM: regulatory protein TetR; KEGG: gtn:GTNG_3165 transcriptional regulator TetR family. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.557 |
Exig_0184 | Exig_0181 | Exig_0184 | Exig_0181 | KEGG: par:Psyc_2123 hypothetical protein. | PFAM: amino acid permease-associated region; KEGG: gtn:GTNG_3167 probable amino acid permease. | 0.448 |
Exig_0184 | Exig_0183 | Exig_0184 | Exig_0183 | KEGG: par:Psyc_2123 hypothetical protein. | PFAM: regulatory protein TetR; KEGG: gtn:GTNG_3165 transcriptional regulator TetR family. | 0.629 |
Exig_0184 | kynA | Exig_0184 | Exig_0180 | KEGG: par:Psyc_2123 hypothetical protein. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.421 |
Exig_0184 | kynB | Exig_0184 | Exig_0179 | KEGG: par:Psyc_2123 hypothetical protein. | Arylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.411 |
Exig_0184 | kynU | Exig_0184 | Exig_0182 | KEGG: par:Psyc_2123 hypothetical protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.448 |
Exig_1060 | kynU | Exig_1060 | Exig_0182 | PFAM: aromatic amino acid hydroxylase; KEGG: bcy:Bcer98_3076 aromatic amino acid hydroxylase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.502 |
Exig_1760 | kynU | Exig_1760 | Exig_0182 | PFAM: monooxygenase FAD-binding; KEGG: bxe:Bxe_A0962 putative monooxygenase, FAD-binding. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.489 |
Exig_2191 | kynU | Exig_2191 | Exig_0182 | PFAM: Catalase domain protein; KEGG: bcl:ABC1283 catalase; Belongs to the catalase family. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.903 |
kynA | Exig_0181 | Exig_0180 | Exig_0181 | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | PFAM: amino acid permease-associated region; KEGG: gtn:GTNG_3167 probable amino acid permease. | 0.727 |
kynA | Exig_0183 | Exig_0180 | Exig_0183 | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | PFAM: regulatory protein TetR; KEGG: gtn:GTNG_3165 transcriptional regulator TetR family. | 0.510 |