node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Exig_0659 | hemL1 | Exig_0659 | Exig_0658 | Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: gtn:GTNG_0490 transcriptional regulator Fur family; Belongs to the Fur family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bpu:BPUM_0825 glutamate-1-semialdehyde 2,1-aminomutase. | 0.534 |
Exig_1909 | Exig_2716 | Exig_1909 | Exig_2716 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: lin:lin1922 similar to malonyl CoA-acyl carrier protein transacylase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.490 |
Exig_1909 | guaA | Exig_1909 | Exig_0439 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: lin:lin1922 similar to malonyl CoA-acyl carrier protein transacylase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.448 |
Exig_1909 | hemL1 | Exig_1909 | Exig_0658 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: lin:lin1922 similar to malonyl CoA-acyl carrier protein transacylase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bpu:BPUM_0825 glutamate-1-semialdehyde 2,1-aminomutase. | 0.658 |
Exig_1909 | hemL2 | Exig_1909 | Exig_2134 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: lin:lin1922 similar to malonyl CoA-acyl carrier protein transacylase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gtn:GTNG_2571 glutamate-1-semialdehyde 2,1-aminotransferase. | 0.724 |
Exig_2135 | Exig_2136 | Exig_2135 | Exig_2136 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: oih:OB2066 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.999 |
Exig_2135 | Exig_2716 | Exig_2135 | Exig_2716 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: oih:OB2066 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.495 |
Exig_2135 | hemA | Exig_2135 | Exig_2138 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: oih:OB2066 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.940 |
Exig_2135 | hemC | Exig_2135 | Exig_2137 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: oih:OB2066 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
Exig_2135 | hemE | Exig_2135 | Exig_0699 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: oih:OB2066 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.728 |
Exig_2135 | hemL1 | Exig_2135 | Exig_0658 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: oih:OB2066 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bpu:BPUM_0825 glutamate-1-semialdehyde 2,1-aminomutase. | 0.989 |
Exig_2135 | hemL2 | Exig_2135 | Exig_2134 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: oih:OB2066 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gtn:GTNG_2571 glutamate-1-semialdehyde 2,1-aminotransferase. | 0.997 |
Exig_2136 | Exig_2135 | Exig_2136 | Exig_2135 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: oih:OB2066 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.999 |
Exig_2136 | Exig_2716 | Exig_2136 | Exig_2716 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.522 |
Exig_2136 | hemA | Exig_2136 | Exig_2138 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.956 |
Exig_2136 | hemC | Exig_2136 | Exig_2137 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
Exig_2136 | hemE | Exig_2136 | Exig_0699 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.951 |
Exig_2136 | hemL1 | Exig_2136 | Exig_0658 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bpu:BPUM_0825 glutamate-1-semialdehyde 2,1-aminomutase. | 0.706 |
Exig_2136 | hemL2 | Exig_2136 | Exig_2134 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gtn:GTNG_2571 glutamate-1-semialdehyde 2,1-aminotransferase. | 0.933 |
Exig_2716 | Exig_1909 | Exig_2716 | Exig_1909 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: lin:lin1922 similar to malonyl CoA-acyl carrier protein transacylase. | 0.490 |