node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Exig_0068 | Exig_0471 | Exig_0068 | Exig_0471 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ppg:PputGB1_4905 chaperone DnaJ domain protein. | 0.758 |
Exig_0068 | dnaJ | Exig_0068 | Exig_0782 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.716 |
Exig_0068 | dnaK | Exig_0068 | Exig_0781 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.953 |
Exig_0068 | groL | Exig_0068 | Exig_2768 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.627 |
Exig_0068 | groS | Exig_0068 | Exig_2769 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.681 |
Exig_0068 | grpE | Exig_0068 | Exig_0780 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.812 |
Exig_0068 | hrcA | Exig_0068 | Exig_0779 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.586 |
Exig_0068 | htpG | Exig_0068 | Exig_2981 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.718 |
Exig_0471 | Exig_0068 | Exig_0471 | Exig_0068 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ppg:PputGB1_4905 chaperone DnaJ domain protein. | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | 0.758 |
Exig_0471 | Exig_2335 | Exig_0471 | Exig_2335 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ppg:PputGB1_4905 chaperone DnaJ domain protein. | TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: btl:BALH_4512 NifU family protein. | 0.401 |
Exig_0471 | clpB | Exig_0471 | Exig_0472 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ppg:PputGB1_4905 chaperone DnaJ domain protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.942 |
Exig_0471 | dnaK | Exig_0471 | Exig_0781 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ppg:PputGB1_4905 chaperone DnaJ domain protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.998 |
Exig_0471 | groL | Exig_0471 | Exig_2768 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ppg:PputGB1_4905 chaperone DnaJ domain protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.838 |
Exig_0471 | groS | Exig_0471 | Exig_2769 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ppg:PputGB1_4905 chaperone DnaJ domain protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.641 |
Exig_0471 | grpE | Exig_0471 | Exig_0780 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ppg:PputGB1_4905 chaperone DnaJ domain protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.963 |
Exig_0471 | hrcA | Exig_0471 | Exig_0779 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ppg:PputGB1_4905 chaperone DnaJ domain protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.715 |
Exig_0471 | htpG | Exig_0471 | Exig_2981 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ppg:PputGB1_4905 chaperone DnaJ domain protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.955 |
Exig_2335 | Exig_0471 | Exig_2335 | Exig_0471 | TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: btl:BALH_4512 NifU family protein. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ppg:PputGB1_4905 chaperone DnaJ domain protein. | 0.401 |
Exig_2335 | dnaJ | Exig_2335 | Exig_0782 | TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: btl:BALH_4512 NifU family protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.412 |
Exig_2335 | dnaK | Exig_2335 | Exig_0781 | TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: btl:BALH_4512 NifU family protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.937 |