STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Exig_0961KEGG: bha:BH3387 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topoisomerase I DNA-binding; Toprim sub domain protein. (705 aa)    
Predicted Functional Partners:
Exig_1817
ATP-dependent DNA helicase, RecQ family; KEGG: bsu:BSU23020 ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases.
 
 0.987
Exig_0962
Hypothetical protein.
       0.785
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.702
Exig_1724
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: bsu:BSU18450 glutamate synthase (large subunit).
  
  
 0.692
dinG
DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
  
 0.658
Exig_3037
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
 
 0.634
Exig_1206
PFAM: SMC domain protein; KEGG: lmf:LMOf2365_1666 exonuclease, SbcC family.
  
 0.629
Exig_0963
Hypothetical protein; KEGG: mdo:100014652 similar to erythrocyte membrane protein band 4.1 like 4B.
       0.571
Exig_0960
PFAM: protein of unknown function DUF6 transmembrane; KEGG: gka:GK2915 hypothetical protein.
       0.563
Exig_2847
PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: cpe:CPE1401 probable DNA polymerase III epsilon chain.
   
 
 0.535
Your Current Organism:
Exiguobacterium sibiricum
NCBI taxonomy Id: 262543
Other names: E. sibiricum 255-15, Exiguobacterium sibiricum 255-15, Exiguobacterium sibiricum str. 255-15, Exiguobacterium sibiricum strain 255-15, Exiguobacterium sp. 255-15, Exiguobacterium strain 255-15
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