node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEB42428.1 | AEB42653.1 | VAB18032_06520 | VAB18032_07665 | DNA polymerase ligd, polymerase domain protein; COG3285 Predicted eukaryotic-type DNA primase. | COG1793 ATP-dependent DNA ligase. | 0.801 |
AEB42428.1 | ku | VAB18032_06520 | VAB18032_06510 | DNA polymerase ligd, polymerase domain protein; COG3285 Predicted eukaryotic-type DNA primase. | Ku family containing protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.957 |
AEB42428.1 | ligB | VAB18032_06520 | VAB18032_28881 | DNA polymerase ligd, polymerase domain protein; COG3285 Predicted eukaryotic-type DNA primase. | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.701 |
AEB42653.1 | AEB42428.1 | VAB18032_07665 | VAB18032_06520 | COG1793 ATP-dependent DNA ligase. | DNA polymerase ligd, polymerase domain protein; COG3285 Predicted eukaryotic-type DNA primase. | 0.801 |
AEB42653.1 | AEB43670.1 | VAB18032_07665 | VAB18032_12780 | COG1793 ATP-dependent DNA ligase. | DNA primase, small subunit; COG3285 Predicted eukaryotic-type DNA primase. | 0.811 |
AEB42653.1 | AEB45841.1 | VAB18032_07665 | VAB18032_23715 | COG1793 ATP-dependent DNA ligase. | COG3285 Predicted eukaryotic-type DNA primase. | 0.811 |
AEB42653.1 | AEB46650.1 | VAB18032_07665 | VAB18032_27886 | COG1793 ATP-dependent DNA ligase. | DNA polymerase III subunit beta; COG0789 Predicted transcriptional regulators. | 0.733 |
AEB42653.1 | AEB47977.1 | VAB18032_07665 | VAB18032_04475 | COG1793 ATP-dependent DNA ligase. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.733 |
AEB42653.1 | ku | VAB18032_07665 | VAB18032_06510 | COG1793 ATP-dependent DNA ligase. | Ku family containing protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.825 |
AEB42653.1 | ligA | VAB18032_07665 | VAB18032_11080 | COG1793 ATP-dependent DNA ligase. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.453 |
AEB42653.1 | ligB | VAB18032_07665 | VAB18032_28881 | COG1793 ATP-dependent DNA ligase. | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.751 |
AEB42653.1 | polA | VAB18032_07665 | VAB18032_26230 | COG1793 ATP-dependent DNA ligase. | DNA polymerase i; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.699 |
AEB43670.1 | AEB42653.1 | VAB18032_12780 | VAB18032_07665 | DNA primase, small subunit; COG3285 Predicted eukaryotic-type DNA primase. | COG1793 ATP-dependent DNA ligase. | 0.811 |
AEB43670.1 | ku | VAB18032_12780 | VAB18032_06510 | DNA primase, small subunit; COG3285 Predicted eukaryotic-type DNA primase. | Ku family containing protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.883 |
AEB43670.1 | ligB | VAB18032_12780 | VAB18032_28881 | DNA primase, small subunit; COG3285 Predicted eukaryotic-type DNA primase. | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.743 |
AEB45841.1 | AEB42653.1 | VAB18032_23715 | VAB18032_07665 | COG3285 Predicted eukaryotic-type DNA primase. | COG1793 ATP-dependent DNA ligase. | 0.811 |
AEB45841.1 | ku | VAB18032_23715 | VAB18032_06510 | COG3285 Predicted eukaryotic-type DNA primase. | Ku family containing protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.884 |
AEB45841.1 | ligB | VAB18032_23715 | VAB18032_28881 | COG3285 Predicted eukaryotic-type DNA primase. | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.743 |
AEB46650.1 | AEB42653.1 | VAB18032_27886 | VAB18032_07665 | DNA polymerase III subunit beta; COG0789 Predicted transcriptional regulators. | COG1793 ATP-dependent DNA ligase. | 0.733 |
AEB46650.1 | AEB47977.1 | VAB18032_27886 | VAB18032_04475 | DNA polymerase III subunit beta; COG0789 Predicted transcriptional regulators. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.925 |