| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PTO0219 | PTO0220 | PTO0219 | PTO0220 | GTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.970 |
| PTO0219 | mptD | PTO0219 | PTO0218 | GTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD). | 0.957 |
| PTO0220 | PTO0219 | PTO0220 | PTO0219 | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | GTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.970 |
| PTO0220 | PTO0236 | PTO0220 | PTO0236 | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | GTP binding protein; GTP1/OBG family. | 0.650 |
| PTO0220 | PTO0251 | PTO0220 | PTO0251 | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | Putative RNA-binding protein; Contains S1 and KH domains. | 0.669 |
| PTO0220 | PTO0668 | PTO0220 | PTO0668 | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | Nop56p-related protein; Ribosomal biogenesis. | 0.808 |
| PTO0220 | PTO0879 | PTO0220 | PTO0879 | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | GTP-binding protein. | 0.623 |
| PTO0220 | mptD | PTO0220 | PTO0218 | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD). | 0.937 |
| PTO0220 | pus10 | PTO0220 | PTO0390 | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | Hypothetical conserved protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | 0.648 |
| PTO0220 | truA | PTO0220 | PTO0780 | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.658 |
| PTO0220 | truB | PTO0220 | PTO0667 | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | tRNA pseudouridine 55 synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.703 |
| PTO0220 | truD | PTO0220 | PTO0505 | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | Conserved hypothetical protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.642 |
| PTO0236 | PTO0220 | PTO0236 | PTO0220 | GTP binding protein; GTP1/OBG family. | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.650 |
| PTO0236 | PTO0668 | PTO0236 | PTO0668 | GTP binding protein; GTP1/OBG family. | Nop56p-related protein; Ribosomal biogenesis. | 0.757 |
| PTO0236 | PTO0879 | PTO0236 | PTO0879 | GTP binding protein; GTP1/OBG family. | GTP-binding protein. | 0.521 |
| PTO0236 | truB | PTO0236 | PTO0667 | GTP binding protein; GTP1/OBG family. | tRNA pseudouridine 55 synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.473 |
| PTO0251 | PTO0220 | PTO0251 | PTO0220 | Putative RNA-binding protein; Contains S1 and KH domains. | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.669 |
| PTO0251 | PTO0668 | PTO0251 | PTO0668 | Putative RNA-binding protein; Contains S1 and KH domains. | Nop56p-related protein; Ribosomal biogenesis. | 0.999 |
| PTO0251 | PTO0879 | PTO0251 | PTO0879 | Putative RNA-binding protein; Contains S1 and KH domains. | GTP-binding protein. | 0.644 |
| PTO0251 | truA | PTO0251 | PTO0780 | Putative RNA-binding protein; Contains S1 and KH domains. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.603 |