node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PTO0199 | dnaG | PTO0199 | PTO0617 | Archaeal hypothetical cytosolic protein; Belongs to the UPF0147 family. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.578 |
PTO0199 | endA | PTO0199 | PTO0518 | Archaeal hypothetical cytosolic protein; Belongs to the UPF0147 family. | tRNA-intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity). | 0.559 |
PTO0199 | rpl29 | PTO0199 | PTO0647 | Archaeal hypothetical cytosolic protein; Belongs to the UPF0147 family. | Large subunit ribosomal protein S29P; Belongs to the universal ribosomal protein uL29 family. | 0.585 |
PTO0199 | rps27ae | PTO0199 | PTO0870 | Archaeal hypothetical cytosolic protein; Belongs to the UPF0147 family. | Small subunit ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.496 |
PTO0404 | cca | PTO0404 | PTO0535 | Hypothetical DUF75 protein. | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | 0.515 |
PTO0404 | dnaG | PTO0404 | PTO0617 | Hypothetical DUF75 protein. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.635 |
PTO0404 | endA | PTO0404 | PTO0518 | Hypothetical DUF75 protein. | tRNA-intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity). | 0.487 |
PTO0404 | nac | PTO0404 | PTO0534 | Hypothetical DUF75 protein. | Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. | 0.633 |
PTO0404 | rpl29 | PTO0404 | PTO0647 | Hypothetical DUF75 protein. | Large subunit ribosomal protein S29P; Belongs to the universal ribosomal protein uL29 family. | 0.481 |
PTO0404 | rps27ae | PTO0404 | PTO0870 | Hypothetical DUF75 protein. | Small subunit ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.416 |
PTO0404 | spt5 | PTO0404 | PTO0445 | Hypothetical DUF75 protein. | Hypothetical transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.512 |
PTO0519 | PTO0520 | PTO0519 | PTO0520 | Hypothetical protein. | Zinc finger protein. | 0.454 |
PTO0519 | endA | PTO0519 | PTO0518 | Hypothetical protein. | tRNA-intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity). | 0.921 |
PTO0520 | PTO0519 | PTO0520 | PTO0519 | Zinc finger protein. | Hypothetical protein. | 0.454 |
PTO0520 | endA | PTO0520 | PTO0518 | Zinc finger protein. | tRNA-intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity). | 0.643 |
cca | PTO0404 | PTO0535 | PTO0404 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | Hypothetical DUF75 protein. | 0.515 |
cca | dnaG | PTO0535 | PTO0617 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.638 |
cca | endA | PTO0535 | PTO0518 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | tRNA-intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity). | 0.511 |
cca | nac | PTO0535 | PTO0534 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. | 0.964 |
cca | spt5 | PTO0535 | PTO0445 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | Hypothetical transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.672 |