node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PTO0336 | moaA | PTO0336 | PTO1057 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Putative molybdopterin cofactor synthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.800 |
PTO0336 | mptA | PTO0336 | PTO1009 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Hypothetical conserved protein DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.843 |
PTO0336 | ndk | PTO0336 | PTO1283 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.912 |
PTO0336 | ribA | PTO0336 | PTO0570 | Pyruvate kinase; Belongs to the pyruvate kinase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.800 |
PTO0692 | mptA | PTO0692 | PTO1009 | Ferripyochelin binding protein. | Hypothetical conserved protein DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.607 |
PTO1005 | PTO1006 | PTO1005 | PTO1006 | Hypothetical protein. | Monocarboxylic acid/H+ symporter MctP; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.831 |
PTO1005 | PTO1007 | PTO1005 | PTO1007 | Hypothetical protein. | Hypothetical protein. | 0.596 |
PTO1005 | mptA | PTO1005 | PTO1009 | Hypothetical protein. | Hypothetical conserved protein DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.596 |
PTO1005 | pfdB | PTO1005 | PTO1008 | Hypothetical protein. | Hypothetical prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.596 |
PTO1006 | PTO1005 | PTO1006 | PTO1005 | Monocarboxylic acid/H+ symporter MctP; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Hypothetical protein. | 0.831 |
PTO1006 | PTO1007 | PTO1006 | PTO1007 | Monocarboxylic acid/H+ symporter MctP; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Hypothetical protein. | 0.596 |
PTO1006 | mptA | PTO1006 | PTO1009 | Monocarboxylic acid/H+ symporter MctP; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Hypothetical conserved protein DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.596 |
PTO1006 | pfdB | PTO1006 | PTO1008 | Monocarboxylic acid/H+ symporter MctP; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Hypothetical prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.596 |
PTO1007 | PTO1005 | PTO1007 | PTO1005 | Hypothetical protein. | Hypothetical protein. | 0.596 |
PTO1007 | PTO1006 | PTO1007 | PTO1006 | Hypothetical protein. | Monocarboxylic acid/H+ symporter MctP; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.596 |
PTO1007 | mptA | PTO1007 | PTO1009 | Hypothetical protein. | Hypothetical conserved protein DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.773 |
PTO1007 | pfdB | PTO1007 | PTO1008 | Hypothetical protein. | Hypothetical prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.838 |
PTO1064 | mptA | PTO1064 | PTO1009 | 6-pyruvoyltetrahydrobiopterin synthase. | Hypothetical conserved protein DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.610 |
PTO1064 | pfdB | PTO1064 | PTO1008 | 6-pyruvoyltetrahydrobiopterin synthase. | Hypothetical prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.518 |
moaA | PTO0336 | PTO1057 | PTO0336 | Putative molybdopterin cofactor synthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.800 |