STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (318 aa)    
Predicted Functional Partners:
nadE
Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase:NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.962
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.946
cobB
Silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.922
AAZ60239.1
NUDIX hydrolase.
     
 0.906
AAZ60413.1
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
  
 0.774
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
    
 0.661
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
       0.606
AAZ61803.1
Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+)/phosphate acetyltransferase.
   
 
 0.598
AAZ62208.1
Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+)., Phosphate acetyltransferase.
   
 
 0.598
PntAb
pntAb, RSc2732; NAD(P) transhydrogenase subunit alpha.
     
 0.557
Your Current Organism:
Cupriavidus pinatubonensis
NCBI taxonomy Id: 264198
Other names: C. pinatubonensis JMP134, Cupriavidus necator JMP134, Cupriavidus pinatubonensis JMP134, Ralstonia eutropha JMP134, Ralstonia eutropha str. JMP134, Ralstonia eutropha strain JMP134, Ralstonia sp. JMP134, Wautersia eutropha JMP134
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