STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (273 aa)    
Predicted Functional Partners:
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 0.995
AAZ64315.1
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
 0.973
AAZ63635.1
Branched chain amino acid aminotransferase apoenzyme.
    
 0.924
AAZ64020.1
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.918
AAZ64085.1
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.918
ilvD1
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
    
 0.913
ilvD2
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
    
 0.913
AAZ63306.1
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
    
 0.913
AAZ62142.1
Binding-protein-dependent transport systems inner membrane component.
  
    0.800
AAZ62143.1
ABC transporter related protein.
       0.787
Your Current Organism:
Cupriavidus pinatubonensis
NCBI taxonomy Id: 264198
Other names: C. pinatubonensis JMP134, Cupriavidus necator JMP134, Cupriavidus pinatubonensis JMP134, Ralstonia eutropha JMP134, Ralstonia eutropha str. JMP134, Ralstonia eutropha strain JMP134, Ralstonia sp. JMP134, Wautersia eutropha JMP134
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.