node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAZ60437.1 | dnaK | Reut_A1059 | Reut_A2785 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.864 |
AAZ60437.1 | groS | Reut_A1059 | Reut_A2657 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.402 |
AAZ63699.1 | AAZ64540.1 | Reut_B4346 | Reut_B5194 | Heat shock protein DnaJ, N-terminal. | Chaperonin Cpn60/TCP-1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 0.801 |
AAZ63699.1 | clpB | Reut_B4346 | Reut_A1980 | Heat shock protein DnaJ, N-terminal. | AAA ATPase, central region:Clp, N terminal; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.659 |
AAZ63699.1 | dnaK | Reut_B4346 | Reut_A2785 | Heat shock protein DnaJ, N-terminal. | Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.964 |
AAZ63699.1 | groL | Reut_B4346 | Reut_A2656 | Heat shock protein DnaJ, N-terminal. | Chaperonin Cpn60/TCP-1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.802 |
AAZ63699.1 | groS | Reut_B4346 | Reut_A2657 | Heat shock protein DnaJ, N-terminal. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.664 |
AAZ63699.1 | grpE | Reut_B4346 | Reut_A1040 | Heat shock protein DnaJ, N-terminal. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.881 |
AAZ63699.1 | htpG | Reut_B4346 | Reut_A2342 | Heat shock protein DnaJ, N-terminal. | Heat shock protein Hsp90:ATP-binding region, ATPase-like protein; Molecular chaperone. Has ATPase activity. | 0.924 |
AAZ64074.1 | AAZ64540.1 | Reut_B4726 | Reut_B5194 | DnaJ central region:Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal. | Chaperonin Cpn60/TCP-1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | 0.773 |
AAZ64074.1 | clpB | Reut_B4726 | Reut_A1980 | DnaJ central region:Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal. | AAA ATPase, central region:Clp, N terminal; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.680 |
AAZ64074.1 | dnaK | Reut_B4726 | Reut_A2785 | DnaJ central region:Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal. | Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.978 |
AAZ64074.1 | groL | Reut_B4726 | Reut_A2656 | DnaJ central region:Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal. | Chaperonin Cpn60/TCP-1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.853 |
AAZ64074.1 | groS | Reut_B4726 | Reut_A2657 | DnaJ central region:Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.744 |
AAZ64074.1 | grpE | Reut_B4726 | Reut_A1040 | DnaJ central region:Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.925 |
AAZ64074.1 | htpG | Reut_B4726 | Reut_A2342 | DnaJ central region:Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal. | Heat shock protein Hsp90:ATP-binding region, ATPase-like protein; Molecular chaperone. Has ATPase activity. | 0.950 |
AAZ64540.1 | AAZ63699.1 | Reut_B5194 | Reut_B4346 | Chaperonin Cpn60/TCP-1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | Heat shock protein DnaJ, N-terminal. | 0.801 |
AAZ64540.1 | AAZ64074.1 | Reut_B5194 | Reut_B4726 | Chaperonin Cpn60/TCP-1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | DnaJ central region:Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal. | 0.773 |
AAZ64540.1 | clpB | Reut_B5194 | Reut_A1980 | Chaperonin Cpn60/TCP-1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | AAA ATPase, central region:Clp, N terminal; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.618 |
AAZ64540.1 | dnaJ | Reut_B5194 | Reut_A2784 | Chaperonin Cpn60/TCP-1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family. | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.769 |