STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsdAD-serine ammonia-lyase; Belongs to the serine/threonine dehydratase family. DsdA subfamily. (443 aa)    
Predicted Functional Partners:
AAZ62691.1
L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
    
 0.913
AAZ64155.1
L-serine ammonia-lyase.
    
 0.913
AAZ64179.1
L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
    
 0.913
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
 0.907
ilvA-2
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
 0.907
Dsd
Dsd, RSp1185; probable D-serine deaminase (d-serine dehydratase) protein.
     
  0.900
AAZ59885.1
Glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
     
 0.804
AAZ59534.1
Glyoxylate/hydroxypyruvate reductase; 6-phosphogluconate dehydrogenase, NAD-binding protein:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein.
     
  0.800
AAZ60271.1
Glyoxylate/hydroxypyruvate reductase; 6-phosphogluconate dehydrogenase, NAD-binding protein:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein.
     
  0.800
AAZ61644.1
Glyoxylate/hydroxypyruvate/2-ketogluconate reductase; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein.
     
  0.800
Your Current Organism:
Cupriavidus pinatubonensis
NCBI taxonomy Id: 264198
Other names: C. pinatubonensis JMP134, Cupriavidus necator JMP134, Cupriavidus pinatubonensis JMP134, Ralstonia eutropha JMP134, Ralstonia eutropha str. JMP134, Ralstonia eutropha strain JMP134, Ralstonia sp. JMP134, Wautersia eutropha JMP134
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