node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAZ60238.1 | AAZ64176.1 | Reut_A0859 | Reut_B4828 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Sarcosine oxidase, alpha subunit, heterotetrameric; Belongs to the GcvT family. | 0.937 |
AAZ60238.1 | gcvP | Reut_A0859 | Reut_A3331 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.963 |
AAZ60238.1 | glyA1 | Reut_A0859 | Reut_A0790 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.929 |
AAZ60238.1 | glyA2 | Reut_A0859 | Reut_B4822 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.929 |
AAZ60238.1 | kbl | Reut_A0859 | Reut_B4803 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.919 |
AAZ60676.1 | AAZ61409.1 | Reut_A1306 | Reut_A2045 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.982 |
AAZ60676.1 | AAZ64154.1 | Reut_A1306 | Reut_B4806 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein. | 0.990 |
AAZ60676.1 | AAZ64176.1 | Reut_A1306 | Reut_B4828 | Dihydrolipoamide dehydrogenase. | Sarcosine oxidase, alpha subunit, heterotetrameric; Belongs to the GcvT family. | 0.967 |
AAZ60676.1 | gcvH | Reut_A1306 | Reut_A3330 | Dihydrolipoamide dehydrogenase. | Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.995 |
AAZ60676.1 | gcvP | Reut_A1306 | Reut_A3331 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.984 |
AAZ60676.1 | gcvT | Reut_A1306 | Reut_A3329 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.990 |
AAZ60676.1 | glyA1 | Reut_A1306 | Reut_A0790 | Dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.955 |
AAZ60676.1 | glyA2 | Reut_A1306 | Reut_B4822 | Dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.949 |
AAZ61409.1 | AAZ60676.1 | Reut_A2045 | Reut_A1306 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.982 |
AAZ61409.1 | AAZ64154.1 | Reut_A2045 | Reut_B4806 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein. | 0.955 |
AAZ61409.1 | AAZ64176.1 | Reut_A2045 | Reut_B4828 | Dihydrolipoamide dehydrogenase. | Sarcosine oxidase, alpha subunit, heterotetrameric; Belongs to the GcvT family. | 0.781 |
AAZ61409.1 | gcvH | Reut_A2045 | Reut_A3330 | Dihydrolipoamide dehydrogenase. | Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.975 |
AAZ61409.1 | gcvP | Reut_A2045 | Reut_A3331 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.965 |
AAZ61409.1 | gcvT | Reut_A2045 | Reut_A3329 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.954 |
AAZ61409.1 | glyA1 | Reut_A2045 | Reut_A0790 | Dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.918 |