node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
eno | gapA | CF0051 | CF0890 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glyceraldehyde 3-phosphate dehydrogenase; EC 1.2.1.12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.911 |
eno | pfkA1 | CF0051 | CF0393 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase beta chain; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.682 |
eno | pfkA2 | CF0051 | CF0395 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase beta chain; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily. | 0.682 |
eno | pgi | CF0051 | CF0280 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glucose-6-phosphate isomerase; EC 5.3.1.9. | 0.967 |
eno | pgmA | CF0051 | CF0110 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.974 |
eno | pyk | CF0051 | CF0336 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Pyruvate kinase; EC 2.7.1.40; Belongs to the pyruvate kinase family. | 0.998 |
eno | talA | CF0051 | CF0322 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.889 |
eno | tkt | CF0051 | CF0141 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Transketolase; EC 2.2.1.1; Belongs to the transketolase family. | 0.934 |
eno | tpiS | CF0051 | CF0695 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.916 |
eno | zwf | CF0051 | CF0468 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.835 |
gapA | eno | CF0890 | CF0051 | Glyceraldehyde 3-phosphate dehydrogenase; EC 1.2.1.12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.911 |
gapA | pfkA1 | CF0890 | CF0393 | Glyceraldehyde 3-phosphate dehydrogenase; EC 1.2.1.12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase beta chain; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.616 |
gapA | pfkA2 | CF0890 | CF0395 | Glyceraldehyde 3-phosphate dehydrogenase; EC 1.2.1.12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase beta chain; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily. | 0.616 |
gapA | pgi | CF0890 | CF0280 | Glyceraldehyde 3-phosphate dehydrogenase; EC 1.2.1.12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Glucose-6-phosphate isomerase; EC 5.3.1.9. | 0.947 |
gapA | pgmA | CF0890 | CF0110 | Glyceraldehyde 3-phosphate dehydrogenase; EC 1.2.1.12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.670 |
gapA | pyk | CF0890 | CF0336 | Glyceraldehyde 3-phosphate dehydrogenase; EC 1.2.1.12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Pyruvate kinase; EC 2.7.1.40; Belongs to the pyruvate kinase family. | 0.928 |
gapA | talA | CF0890 | CF0322 | Glyceraldehyde 3-phosphate dehydrogenase; EC 1.2.1.12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.880 |
gapA | tkt | CF0890 | CF0141 | Glyceraldehyde 3-phosphate dehydrogenase; EC 1.2.1.12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Transketolase; EC 2.2.1.1; Belongs to the transketolase family. | 0.918 |
gapA | tpiS | CF0890 | CF0695 | Glyceraldehyde 3-phosphate dehydrogenase; EC 1.2.1.12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.994 |
gapA | zwf | CF0890 | CF0468 | Glyceraldehyde 3-phosphate dehydrogenase; EC 1.2.1.12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.894 |