STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgkPhosphoglycerate kinase; EC 2.7.2.3; Belongs to the phosphoglycerate kinase family. (403 aa)    
Predicted Functional Partners:
gapA
Glyceraldehyde 3-phosphate dehydrogenase; EC 1.2.1.12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.992
tpiS
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.991
pgmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.973
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.945
pyk
Pyruvate kinase; EC 2.7.1.40; Belongs to the pyruvate kinase family.
  
 
 0.920
pgi
Glucose-6-phosphate isomerase; EC 5.3.1.9.
  
 
 0.846
ygo
Phosphate permease.
  
    0.769
ebp17
Hypothetical protein.
       0.763
tkt
Transketolase; EC 2.2.1.1; Belongs to the transketolase family.
  
 
 0.721
pfkA1
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase beta chain; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
  
 0.632
Your Current Organism:
Chlamydia felis
NCBI taxonomy Id: 264202
Other names: C. felis Fe/C-56, Chlamydia felis Fe/C-56, Chlamydophila felis Fe/C-56
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