STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bd1253Conserved hypothetical protein; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-17-dioic acid hydratase (catechol pathway). (195 aa)    
Predicted Functional Partners:
Bd0294
Fumarylacetoacetate hydrolase family protein; hypothetical protein.
     
  0.900
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.839
sdhA
InterPro: Fumarate reductase/succinate dehydrogenase flavoprotein N-terminal, Succinate dehydrogenase subunit A; hypothetical protein.
  
 
 0.836
Bd1254
Probable phosphoglycerate mutase.
       0.823
sdhB
InterPro: Ferredoxin, succinate dehydrogenase subunit B, succinate dehydrogenase, iron-sulfur protein; hypothetical protein.
  
 
  0.813
sdhC
Putative succinate dehydrogenase subunit C; hypothetical protein.
    
  0.809
fumB
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.804
putA
1-pyrroline-5 carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
 
 0.791
hmgA
Homogentisate 1,2-dioxygenase.
  
  
 0.773
alaS
Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
 
      0.662
Your Current Organism:
Bdellovibrio bacteriovorus HD100
NCBI taxonomy Id: 264462
Other names: B. bacteriovorus HD100, Bdellovibrio bacteriovorus DSM 50701, Bdellovibrio bacteriovorus str. HD100, Bdellovibrio bacteriovorus strain HD100
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