STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exoAExodeoxyribonuclease; InterPro: AP endonucleases family 1, Exodeoxyribonuclease III xth; hypothetical protein. (257 aa)    
Predicted Functional Partners:
nth
Endo III-related endonuclease; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.945
Bd3524
Exodeoxyribonuclease III (EC 3.1.11.2); hypothetical protein.
  
  
 
0.909
Bd0253
DNA methylation and regulatory protein Ada, 3-methyladenine DNA glycosydase; hypothetical protein.
  
 0.797
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.761
lig-2
Lig protein; InterPro: ATP-dependent DNA ligase; hypothetical protein.
 
 
 0.722
rsuA2
Pseudouridylate synthase; Belongs to the pseudouridine synthase RsuA family.
  
    0.645
Bd3264
Putative pseudouridylate synthase; hypothetical protein; Belongs to the pseudouridine synthase RsuA family.
  
    0.645
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.633
mutY
A/G-specific adenine glycosylase; InterPro: HhH-GPD; hypothetical protein.
    
 0.600
Bd3668
Hypothetical protein; InterPro: PAP/25A core domain; hypothetical protein.
       0.542
Your Current Organism:
Bdellovibrio bacteriovorus HD100
NCBI taxonomy Id: 264462
Other names: B. bacteriovorus HD100, Bdellovibrio bacteriovorus DSM 50701, Bdellovibrio bacteriovorus str. HD100, Bdellovibrio bacteriovorus strain HD100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.