node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PRU_0130 | PRU_0131 | PRU_0130 | PRU_0131 | Conserved hypothetical protein; Identified by similarity to GB:BAD47644.1; match to protein family HMM PF08885. | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.787 |
PRU_0131 | PRU_0130 | PRU_0131 | PRU_0130 | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Conserved hypothetical protein; Identified by similarity to GB:BAD47644.1; match to protein family HMM PF08885. | 0.787 |
PRU_0131 | PRU_2334 | PRU_0131 | PRU_2334 | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Putative cell division protein; Annotation based on presence in a gene cluster; identified by similarity to GB:BAD47053.1. | 0.895 |
PRU_0131 | ald | PRU_0131 | PRU_2067 | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Alanine dehydrogenase; Identified by similarity to SP:P17556; match to protein family HMM PF01262; match to protein family HMM PF01488; match to protein family HMM PF02826; match to protein family HMM PF05222; match to protein family HMM TIGR00518; Belongs to the AlaDH/PNT family. | 0.965 |
PRU_0131 | ddl | PRU_0131 | PRU_2235 | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.963 |
PRU_0131 | mraY | PRU_0131 | PRU_2329 | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.968 |
PRU_0131 | murA | PRU_0131 | PRU_2927 | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.802 |
PRU_0131 | murD | PRU_0131 | PRU_2330 | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.899 |
PRU_0131 | murE | PRU_0131 | PRU_2328 | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.980 |
PRU_0131 | murF | PRU_0131 | PRU_2263 | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.928 |
PRU_0131 | murG | PRU_0131 | PRU_2332 | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.857 |
PRU_2334 | PRU_0131 | PRU_2334 | PRU_0131 | Putative cell division protein; Annotation based on presence in a gene cluster; identified by similarity to GB:BAD47053.1. | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.895 |
PRU_2334 | ddl | PRU_2334 | PRU_2235 | Putative cell division protein; Annotation based on presence in a gene cluster; identified by similarity to GB:BAD47053.1. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.778 |
PRU_2334 | mraY | PRU_2334 | PRU_2329 | Putative cell division protein; Annotation based on presence in a gene cluster; identified by similarity to GB:BAD47053.1. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.783 |
PRU_2334 | murD | PRU_2334 | PRU_2330 | Putative cell division protein; Annotation based on presence in a gene cluster; identified by similarity to GB:BAD47053.1. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.952 |
PRU_2334 | murE | PRU_2334 | PRU_2328 | Putative cell division protein; Annotation based on presence in a gene cluster; identified by similarity to GB:BAD47053.1. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.840 |
PRU_2334 | murF | PRU_2334 | PRU_2263 | Putative cell division protein; Annotation based on presence in a gene cluster; identified by similarity to GB:BAD47053.1. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.622 |
PRU_2334 | murG | PRU_2334 | PRU_2332 | Putative cell division protein; Annotation based on presence in a gene cluster; identified by similarity to GB:BAD47053.1. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.979 |
ald | PRU_0131 | PRU_2067 | PRU_0131 | Alanine dehydrogenase; Identified by similarity to SP:P17556; match to protein family HMM PF01262; match to protein family HMM PF01488; match to protein family HMM PF02826; match to protein family HMM PF05222; match to protein family HMM TIGR00518; Belongs to the AlaDH/PNT family. | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.965 |
ddl | PRU_0131 | PRU_2235 | PRU_0131 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.963 |