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ndk protein (Moorella thermoacetica) - STRING interaction network
"ndk" - Nucleoside diphosphate kinase in Moorella thermoacetica
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (139 aa)    
Predicted Functional Partners:
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family (217 aa)
 
  0.954
cmk
annotation not available (229 aa)
   
 
  0.946
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (885 aa)
   
 
  0.940
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1141 aa)
   
  0.937
Moth_0003
Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...] (374 aa)
     
  0.934
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1164 aa)
   
 
  0.933
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (313 aa)
   
  0.932
Moth_2099
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP (210 aa)
   
  0.931
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP (240 aa)
     
 
  0.931
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction (747 aa)
   
 
  0.931
Your Current Organism:
Moorella thermoacetica
NCBI taxonomy Id: 264732
Other names: M. thermoacetica ATCC 39073, Moorella thermoacetica, Moorella thermoacetica ATCC 39073, Moorella thermoacetica ATCC39073, Moorella thermoacetica str. ATCC 39073, Moorella thermoacetica strain ATCC 39073
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