node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Moth_0575 | guaA | Moth_0575 | Moth_2105 | DNA internalization-related competence protein ComEC/Rec2. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.404 |
Moth_0575 | nadD | Moth_0575 | Moth_0564 | DNA internalization-related competence protein ComEC/Rec2. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.464 |
Moth_0575 | obg | Moth_0575 | Moth_0561 | DNA internalization-related competence protein ComEC/Rec2. | Small GTP-binding protein domain; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.462 |
Moth_0575 | proA | Moth_0575 | Moth_0563 | DNA internalization-related competence protein ComEC/Rec2. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.662 |
Moth_0575 | proB | Moth_0575 | Moth_0562 | DNA internalization-related competence protein ComEC/Rec2. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.661 |
Moth_0575 | proC | Moth_0575 | Moth_0860 | DNA internalization-related competence protein ComEC/Rec2. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.636 |
Moth_0575 | ribBA | Moth_0575 | Moth_0917 | DNA internalization-related competence protein ComEC/Rec2. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.640 |
Moth_1785 | guaA | Moth_1785 | Moth_2105 | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.565 |
Moth_1785 | proA | Moth_1785 | Moth_0563 | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.540 |
Moth_1785 | proB | Moth_1785 | Moth_0562 | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.715 |
argD | guaA | Moth_2287 | Moth_2105 | Acetylornithine aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.565 |
argD | proA | Moth_2287 | Moth_0563 | Acetylornithine aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.540 |
argD | proB | Moth_2287 | Moth_0562 | Acetylornithine aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.715 |
guaA | Moth_0575 | Moth_2105 | Moth_0575 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA internalization-related competence protein ComEC/Rec2. | 0.404 |
guaA | Moth_1785 | Moth_2105 | Moth_1785 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.565 |
guaA | argD | Moth_2105 | Moth_2287 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Acetylornithine aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.565 |
guaA | obg | Moth_2105 | Moth_0561 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Small GTP-binding protein domain; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.563 |
guaA | proA | Moth_2105 | Moth_0563 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.670 |
guaA | proB | Moth_2105 | Moth_0562 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.609 |
guaA | proC | Moth_2105 | Moth_0860 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.701 |