node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Moth_0705 | Moth_2106 | Moth_0705 | Moth_2106 | Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.874 |
Moth_0705 | ade | Moth_0705 | Moth_0463 | Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.692 |
Moth_0705 | adk | Moth_0705 | Moth_2439 | Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.421 |
Moth_0705 | guaA | Moth_0705 | Moth_2105 | Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.709 |
Moth_0705 | guaB | Moth_0705 | Moth_1108 | Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.541 |
Moth_2099 | Moth_2106 | Moth_2099 | Moth_2106 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.902 |
Moth_2099 | adk | Moth_2099 | Moth_2439 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.946 |
Moth_2099 | guaA | Moth_2099 | Moth_2105 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.986 |
Moth_2099 | guaB | Moth_2099 | Moth_1108 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.759 |
Moth_2099 | purA | Moth_2099 | Moth_2309 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.411 |
Moth_2099 | purH | Moth_2099 | Moth_2044 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.412 |
Moth_2099 | tilS | Moth_2099 | Moth_0104 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | tRNA(Ile)-lysidine synthetase-like protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.550 |
Moth_2106 | Moth_0705 | Moth_2106 | Moth_0705 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | 0.874 |
Moth_2106 | Moth_2099 | Moth_2106 | Moth_2099 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.902 |
Moth_2106 | ade | Moth_2106 | Moth_0463 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.888 |
Moth_2106 | adk | Moth_2106 | Moth_2439 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.962 |
Moth_2106 | ftsH | Moth_2106 | Moth_0105 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.883 |
Moth_2106 | guaA | Moth_2106 | Moth_2105 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.992 |
Moth_2106 | guaB | Moth_2106 | Moth_1108 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.932 |
Moth_2106 | purA | Moth_2106 | Moth_2309 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.920 |