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fmt protein (Methylobacillus flagellatus) - STRING interaction network
"fmt" - methionyl-tRNA formyltransferase in Methylobacillus flagellatus
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Predicted Interactions
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textmining
co-expression
protein homology
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fmtmethionyl-tRNA formyltransferase; Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by- (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (308 aa)    
Predicted Functional Partners:
Mfla_0187
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (167 aa)
 
 
  0.986
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (289 aa)
 
 
  0.969
metG1
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (692 aa)
   
 
  0.962
Mfla_0921
methionyl-tRNA synthetase (692 aa)
   
 
  0.962
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (430 aa)
     
 
  0.923
Mfla_0914
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (167 aa)
   
 
  0.912
Mfla_0914
Dihydrofolate reductase (167 aa)
   
 
  0.912
Mfla_2509
B12-dependent methionine synthase (1262 aa)
     
 
  0.903
Mfla_0439
Aminomethyltransferase (372 aa)
     
 
  0.902
purT
Phosphoribosylglycinamide formyltransferase 2; Catalyzes two reactions- the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR; the second, a side reaction, is the production of acetyl phosphate and ADP from acetate and ATP (400 aa)
     
 
    0.900
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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