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hisB protein (Methylobacillus flagellatus) - STRING interaction network
"hisB" - Imidazoleglycerol-phosphate dehydratase in Methylobacillus flagellatus
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
hisBImidazoleglycerol-phosphate dehydratase (198 aa)    
Predicted Functional Partners:
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (432 aa)
 
  0.999
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (252 aa)
 
 
  0.999
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (214 aa)
 
 
  0.999
Mfla_0249
Histidinol-phosphate aminotransferase (354 aa)
 
  0.997
hisA
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (247 aa)
   
  0.995
Mfla_1684
Histidinol-phosphate aminotransferase (369 aa)
 
  0.994
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (130 aa)
 
   
  0.992
hisG
ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (214 aa)
 
   
  0.976
hisE
phosphoribosyl-ATP pyrophosphatase (106 aa)
 
   
  0.975
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (526 aa)
   
   
  0.836
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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