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hemF protein (Methylobacillus flagellatus) - STRING interaction network
"hemF" - Coproporphyrinogen III oxidase in Methylobacillus flagellatus
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Predicted Interactions
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textmining
co-expression
protein homology
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hemFCoproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX (302 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (354 aa)
 
 
  0.991
Mfla_0040
Coproporphyrinogen III oxidase, anaerobic (384 aa)
   
 
  0.875
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX (344 aa)
 
   
  0.838
tsaC
SUA5/yciO/yrdC-like protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate (180 aa)
   
        0.835
purD
Phosphoribosylamine--glycine ligase (422 aa)
   
        0.827
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (310 aa)
   
   
  0.784
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (414 aa)
   
   
  0.679
purH
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (528 aa)
   
        0.650
Mfla_0345
Amino acid permease-associated region (468 aa)
         
  0.616
cysG
uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme (493 aa)
     
   
  0.587
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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