STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBTIGRFAM: homoserine kinase; PRIAM: Homoserine kinase; PFAM: aminoglycoside phosphotransferase; KEGG: neu:NE1471 putative homoserine kinase protein; COGs: COG2334 Putative homoserine kinase type II (protein kinase fold) category=R; Belongs to the pseudomonas-type ThrB family. (319 aa)    
Predicted Functional Partners:
Mfla_0905
TIGRFAM: threonine synthase; PRIAM: Threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: dar:Daro_2382 threonine synthase; COGs: COG0498 Threonine synthase category=E.
    
 0.946
Mfla_0904
PRIAM: Homoserine dehydrogenase; PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: eba:ebA4952 homoserine dehydrogenase; COGs: COG0460 Homoserine dehydrogenase category=E.
    
 0.944
Mfla_2509
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.808
ilvE
Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.807
metE
Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
 0.801
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.800
Mfla_0615
PRIAM: Serine O-acetyltransferase; KEGG: neu:NE0575 bacterial transferase hexapeptide repeat; COGs: COG1045 Serine acetyltransferase category=E.
     
  0.800
Mfla_0811
TIGRFAM: serine O-acetyltransferase; PRIAM: Serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; KEGG: tbd:Tbd_1162 serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase category=E.
     
  0.800
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
     
  0.800
Mfla_0360
Hypothetical protein.
  
    0.757
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus KT, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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