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Mfla_1330 protein (Methylobacillus flagellatus) - STRING interaction network
"Mfla_1330" - Primary replicative DNA helicase in Methylobacillus flagellatus
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Mfla_1330Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins (462 aa)    
Predicted Functional Partners:
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (357 aa)
   
  0.974
Mfla_1332
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3’ invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA’s homology-searching function (453 aa)
   
  0.974
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication (576 aa)
 
 
  0.931
priB
Single-strand binding protein/primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS) (99 aa)
     
 
  0.904
Mfla_1572
DNA polymerase III, tau subunit (572 aa)
   
 
  0.893
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box)- 5’-TTATC[CA]A[CA]A-3’. DnaA binds to ATP and to acidic phospholipids (470 aa)
   
 
  0.867
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (75 aa)
 
   
  0.848
Mfla_2547
IstB-like ATP-binding protein (247 aa)
     
 
  0.829
priA
Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA (738 aa)
 
 
  0.828
Mfla_0363
ATP-dependent DNA helicase UvrD (731 aa)
 
 
  0.824
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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