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Mfla_1332 protein (Methylobacillus flagellatus) - STRING interaction network
"Mfla_1332" - DNA repair protein RadA in Methylobacillus flagellatus
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Mfla_1332DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3’ invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA’s homology-searching function (453 aa)    
Predicted Functional Partners:
Mfla_1330
Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins (462 aa)
   
  0.974
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (357 aa)
 
        0.902
rplI
50S ribosomal protein L9P; Binds to the 23S rRNA (148 aa)
   
   
  0.751
Mfla_0358
DNA polymerase I (910 aa)
 
   
  0.709
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (75 aa)
              0.707
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (345 aa)
 
   
  0.704
rpsF
SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA (131 aa)
         
  0.697
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5’ and 3’ sides of the lesion. The N-terminal half is responsible for the 3’ incision and the C-terminal half is responsible for the 5’ incision (599 aa)
   
 
  0.685
prmA
50S ribosomal protein L11P methyltransferase; Methylates ribosomal protein L11 (295 aa)
   
        0.649
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3’- to 5’- polarity. Unwinds branched duplex DNA (Y-DNA) (686 aa)
   
 
  0.639
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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