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ligA protein (Methylobacillus flagellatus) - STRING interaction network
"ligA" - DNA ligase, NAD-dependent in Methylobacillus flagellatus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
ligADNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5’-phosphoryl and 3’-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (693 aa)    
Predicted Functional Partners:
Mfla_1402
ZipA-like protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins (438 aa)
              0.883
Mfla_1405
TPR repeat-containing protein (300 aa)
   
        0.862
Mfla_1404
3’(2’),5’-bisphosphate nucleotidase (266 aa)
   
        0.861
smc
Condensin subunit Smc; Required for chromosome condensation and partitioning (1168 aa)
   
   
  0.785
Mfla_0363
ATP-dependent DNA helicase UvrD (731 aa)
 
   
  0.766
leuS
leucyl-tRNA synthetase (817 aa)
   
 
  0.762
Mfla_0358
DNA polymerase I (910 aa)
 
 
  0.726
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (344 aa)
         
  0.703
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy (125 aa)
           
  0.699
Mfla_1120
Ferritin and Dps (156 aa)
       
 
  0.694
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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