STRINGSTRING
Mfla_1448 protein (Methylobacillus flagellatus) - STRING interaction network
"Mfla_1448" - Cytochrome-c oxidase in Methylobacillus flagellatus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfla_1448Cytochrome-c oxidase; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (631 aa)    
Predicted Functional Partners:
Mfla_1449
Cytochrome c oxidase, subunit II (346 aa)
  0.999
Mfla_1293
Cytochrome c oxidase, subunit III (205 aa)
  0.999
Mfla_1295
Ubiquinol oxidase, subunit II (295 aa)
 
  0.998
Mfla_1447
Cytochrome c oxidase, subunit III (203 aa)
          0.977
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (306 aa)
 
 
  0.972
Mfla_1445
Hypothetical protein (300 aa)
 
          0.920
Mfla_1450
Cytochrome c, class I (169 aa)
 
   
  0.908
nuoH
Respiratory-chain NADH dehydrogenase, subunit 1; NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (339 aa)
   
   
  0.890
Mfla_1451
Pyrrolo-quinoline quinone (616 aa)
              0.859
Mfla_0632
Cytochrome c oxidase, cbb3-type, subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (311 aa)
   
 
  0.852
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
Server load: low (6%) [HD]