STRINGSTRING
purA protein (Methylobacillus flagellatus) - STRING interaction network
"purA" - Adenylosuccinate synthetase in Methylobacillus flagellatus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (440 aa)    
Predicted Functional Partners:
purH
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (528 aa)
 
  0.989
Mfla_1141
Inosine-5’-monophosphate dehydrogenase (486 aa)
 
 
  0.988
Mfla_1819
Adenylosuccinate lyase (456 aa)
 
 
  0.987
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (526 aa)
 
   
  0.956
Mfla_1280
Phosphoribosyltransferase (185 aa)
   
 
  0.953
argG
Argininosuccinate synthase (406 aa)
   
 
  0.947
pyrB
Aspartate carbamoyltransferase catalytic subunit (317 aa)
   
 
  0.938
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1297 aa)
   
 
  0.934
Mfla_0887
Phosphoribosylformylglycinamidine synthase (1297 aa)
   
 
  0.934
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates (247 aa)
       
    0.906
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
Server load: low (11%) [HD]