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der protein (Methylobacillus flagellatus) - STRING interaction network
"der" - GTP-binding protein EngA in Methylobacillus flagellatus
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
derGTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis (499 aa)    
Predicted Functional Partners:
rplN
50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (122 aa)
       
 
  0.956
hisS
histidyl-tRNA synthetase (419 aa)
 
   
  0.941
rplA
50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (230 aa)
   
 
  0.928
bamB
Pyrrolo-quinoline quinone; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (390 aa)
 
 
  0.922
Mfla_1616
Hypothetical protein (208 aa)
 
        0.899
rplF
50S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (177 aa)
     
 
  0.893
rlmN
Hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity (362 aa)
 
 
  0.884
hflX
Small GTP-binding protein domain-containing protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (375 aa)
   
  0.850
Mfla_1622
Tetratricopeptide TPR_2 (247 aa)
   
        0.826
Mfla_1872
Ribosomal large subunit pseudouridine synthase B (383 aa)
 
   
  0.824
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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