STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mchMethenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family. (327 aa)    
Predicted Functional Partners:
Mfla_1660
KEGG: mca:MCA3019 methylene tetrahydromethanopterin dehydrogenase/methylenetetrahydrofolate dehydrogenase, putative; COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase category=I.
 
  
 0.993
ffsA
Formylmethanofuran-tetrahydromethanopterin formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.
 
 
 0.993
Mfla_1656
Protein involved in tetrahydromethanopterin-linked formaldehyde oxidation, Orf7; PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mca:MCA2865 ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase category=H.
 
     0.953
Mfla_1659
PFAM: protein of unknown function DUF201; KEGG: mca:MCA2862 hypothetical protein; COGs: COG2232 ATP-dependent carboligase related to biotin carboxylase category=R.
     0.953
Mfla_1657
SSU ribosomal protein S6P modification protein; TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; ATP-grasp domain protein; KEGG: mca:MCA2864 ribosomal protein S6 modification protein, putative; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) category=J; Belongs to the RimK family.
 
     0.951
Mfla_1665
PRIAM: Formylmethanofuran dehydrogenase; PFAM: glutamate synthase, alpha subunit domain protein; KEGG: noc:Noc_0022 formylmethanofuran dehydrogenase; COGs: COG2218 Formylmethanofuran dehydrogenase subunit C category=C.
   
 0.949
Mfla_2364
KEGG: rba:RB9338 conserved hypothetical protein-putative formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S.
 
   
 0.915
Mfla_2524
KEGG: rba:RB9338 conserved hypothetical protein-putative formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S.
 
   
 0.908
Mfla_1652
KEGG: mca:MCA2866 formaldehyde-activating enzyme; COGs: COG1795 Uncharacterized conserved protein category=S.
 
   
 0.892
Mfla_1661
TIGRFAM: beta-ribofuranosylaminobenzene 5'-phosphate synthase family; PFAM: GHMP kinase; KEGG: mca:MCA2861 kinase, GHMP family, putative; COGs: COG1907 archaeal sugar kinases category=R.
 
     0.873
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus KT, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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