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glyA protein (Methylobacillus flagellatus) - STRING interaction network
"glyA" - Serine hydroxymethyltransferase in Methylobacillus flagellatus
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query proteins and first shell of interactors
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (430 aa)    
Predicted Functional Partners:
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (289 aa)
 
  0.994
Mfla_0439
Aminomethyltransferase (372 aa)
 
  0.991
Mfla_0454
Aminomethyltransferase (961 aa)
   
  0.990
purH
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (528 aa)
   
  0.988
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (123 aa)
   
 
  0.976
Mfla_2509
B12-dependent methionine synthase (1262 aa)
     
 
  0.958
Mfla_1890
Phosphoserine phosphatase (302 aa)
   
  0.957
fhs
Formate-tetrahydrofolate ligase (557 aa)
   
  0.954
thyA1
Thymidylate synthase; Provides the sole de novo source of dTMP for DNA biosynthesis (264 aa)
   
 
  0.950
Mfla_0906
Thymidylate synthase (264 aa)
   
 
  0.950
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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