STRINGSTRING
pyrE protein (Methylobacillus flagellatus) - STRING interaction network
"pyrE" - Orotate phosphoribosyltransferase in Methylobacillus flagellatus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (213 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5’-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5’- monophosphate (OMP) to uridine 5’-monophosphate (UMP) (232 aa)
   
  0.994
Mfla_0923
Orotidine 5’-phosphate decarboxylase (232 aa)
   
  0.994
pyrD
Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (337 aa)
   
 
  0.984
carA
Carbamoyl-phosphate synthase small subunit (376 aa)
 
 
  0.920
Mfla_1654
Orotidine 5’-phosphate decarboxylase (209 aa)
   
   
    0.917
pyrB
Aspartate carbamoyltransferase catalytic subunit (317 aa)
   
 
  0.916
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (526 aa)
   
   
  0.863
Mfla_0779
Carbamoyl-phosphate synthase large subunit (1068 aa)
 
 
  0.859
Mfla_2486
G/U mismatch-specific uracil-DNA glycosylase (174 aa)
              0.850
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of ribose 1,5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP (311 aa)
     
 
  0.833
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
Server load: low (7%) [HD]