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thiE protein (Methylobacillus flagellatus) - STRING interaction network
"thiE" - Thiamine-phosphate pyrophosphorylase in Methylobacillus flagellatus
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (209 aa)    
Predicted Functional Partners:
Mfla_2662
Phosphomethylpyrimidine kinase (281 aa)
 
  0.999
Mfla_0853
Phosphomethylpyrimidine kinase (288 aa)
 
  0.999
Mfla_0853
Phosphomethylpyrimidine kinase (288 aa)
 
  0.999
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (318 aa)
 
 
  0.974
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (259 aa)
   
  0.957
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (628 aa)
 
   
  0.922
hemL
Glutamate-1-semialdehyde aminotransferase (428 aa)
   
   
  0.889
Mfla_2665
Hypothetical protein (193 aa)
   
        0.849
Mfla_2638
Thiamine biosynthesis protein ThiS (68 aa)
 
   
  0.791
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (354 aa)
         
  0.687
Your Current Organism:
Methylobacillus flagellatus
NCBI taxonomy Id: 265072
Other names: M. flagellatus, M. flagellatus KT, Methylobacillus, Methylobacillus flagellatus, Methylobacillus flagellatus KT, Methylobacillus flagellatus str. KT, Methylobacillus flagellatus strain KT
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