node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mfla_2752 | Mfla_2753 | Mfla_2752 | Mfla_2753 | Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: dar:Daro_4106 ParB-like partition protein; COGs: COG1475 transcriptional regulators category=K; Belongs to the ParB family. | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: neu:NE2474 ParA family ATPase; COGs: COG1192 ATPases involved in chromosome partitioning category=D. | 0.997 |
Mfla_2752 | mnmE | Mfla_2752 | Mfla_2757 | Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: dar:Daro_4106 ParB-like partition protein; COGs: COG1475 transcriptional regulators category=K; Belongs to the ParB family. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.523 |
Mfla_2752 | mnmG | Mfla_2752 | Mfla_2755 | Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: dar:Daro_4106 ParB-like partition protein; COGs: COG1475 transcriptional regulators category=K; Belongs to the ParB family. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.768 |
Mfla_2752 | rsmG | Mfla_2752 | Mfla_2754 | Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: dar:Daro_4106 ParB-like partition protein; COGs: COG1475 transcriptional regulators category=K; Belongs to the ParB family. | 16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.924 |
Mfla_2753 | Mfla_2752 | Mfla_2753 | Mfla_2752 | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: neu:NE2474 ParA family ATPase; COGs: COG1192 ATPases involved in chromosome partitioning category=D. | Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: dar:Daro_4106 ParB-like partition protein; COGs: COG1475 transcriptional regulators category=K; Belongs to the ParB family. | 0.997 |
Mfla_2753 | mnmG | Mfla_2753 | Mfla_2755 | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: neu:NE2474 ParA family ATPase; COGs: COG1192 ATPases involved in chromosome partitioning category=D. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.714 |
Mfla_2753 | rsmG | Mfla_2753 | Mfla_2754 | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: neu:NE2474 ParA family ATPase; COGs: COG1192 ATPases involved in chromosome partitioning category=D. | 16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.918 |
apt | mnmG | Mfla_2383 | Mfla_2755 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.773 |
apt | rnpA | Mfla_2383 | Mfla_2760 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.408 |
aroB | mnmG | Mfla_2455 | Mfla_2755 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.705 |
atpA | mnmE | Mfla_2746 | Mfla_2757 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.446 |
atpA | mnmG | Mfla_2746 | Mfla_2755 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.668 |
mnmA | mnmE | Mfla_2115 | Mfla_2757 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.814 |
mnmA | mnmG | Mfla_2115 | Mfla_2755 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.819 |
mnmA | rnpA | Mfla_2115 | Mfla_2760 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.441 |
mnmA | rsmG | Mfla_2115 | Mfla_2754 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.465 |
mnmE | Mfla_2752 | Mfla_2757 | Mfla_2752 | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: dar:Daro_4106 ParB-like partition protein; COGs: COG1475 transcriptional regulators category=K; Belongs to the ParB family. | 0.523 |
mnmE | atpA | Mfla_2757 | Mfla_2746 | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | 0.446 |
mnmE | mnmA | Mfla_2757 | Mfla_2115 | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.814 |
mnmE | mnmG | Mfla_2757 | Mfla_2755 | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.996 |