node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mfl090 | SecG | Mfl090 | Mfl068 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.999 |
Mfl090 | rplO | Mfl090 | Mfl141 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.871 |
Mfl090 | rplR | Mfl090 | Mfl139 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.835 |
Mfl090 | rplV | Mfl090 | Mfl128 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.850 |
Mfl090 | rplW | Mfl090 | Mfl125 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.856 |
Mfl090 | rplX | Mfl090 | Mfl134 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.831 |
Mfl090 | rpmC | Mfl090 | Mfl131 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | 50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. | 0.791 |
Mfl090 | rpsE | Mfl090 | Mfl140 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. | 0.845 |
Mfl090 | secA | Mfl090 | Mfl057 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.993 |
Mfl090 | secY | Mfl090 | Mfl142 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |
SecG | Mfl090 | Mfl068 | Mfl090 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | 0.999 |
SecG | rplO | Mfl068 | Mfl141 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.735 |
SecG | rplR | Mfl068 | Mfl139 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.734 |
SecG | rplV | Mfl068 | Mfl128 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.749 |
SecG | rplW | Mfl068 | Mfl125 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.735 |
SecG | rplX | Mfl068 | Mfl134 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.733 |
SecG | rpmC | Mfl068 | Mfl131 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. | 0.737 |
SecG | secA | Mfl068 | Mfl057 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.999 |
SecG | secY | Mfl068 | Mfl142 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |
rplO | Mfl090 | Mfl141 | Mfl090 | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | 0.871 |