node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mfl175 | Mfl278 | Mfl175 | Mfl278 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Guanosine-3', 5'-bis(diphosphate)3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.916 |
Mfl175 | Mfl528 | Mfl175 | Mfl528 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.910 |
Mfl175 | NrdF | Mfl175 | Mfl530 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Ribonucleoside-diphosphate reductase beta chain. | 0.913 |
Mfl175 | adk | Mfl175 | Mfl144 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.931 |
Mfl175 | gmk | Mfl175 | Mfl195 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.925 |
Mfl278 | Mfl175 | Mfl278 | Mfl175 | Guanosine-3', 5'-bis(diphosphate)3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.916 |
Mfl278 | Mfl528 | Mfl278 | Mfl528 | Guanosine-3', 5'-bis(diphosphate)3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.907 |
Mfl278 | NrdF | Mfl278 | Mfl530 | Guanosine-3', 5'-bis(diphosphate)3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-diphosphate reductase beta chain. | 0.900 |
Mfl278 | dnaG | Mfl278 | Mfl269 | Guanosine-3', 5'-bis(diphosphate)3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.472 |
Mfl278 | gmk | Mfl278 | Mfl195 | Guanosine-3', 5'-bis(diphosphate)3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.934 |
Mfl528 | Mfl175 | Mfl528 | Mfl175 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.910 |
Mfl528 | Mfl278 | Mfl528 | Mfl278 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Guanosine-3', 5'-bis(diphosphate)3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.907 |
Mfl528 | NrdF | Mfl528 | Mfl530 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase beta chain. | 0.999 |
Mfl528 | adk | Mfl528 | Mfl144 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.922 |
Mfl528 | cmk | Mfl528 | Mfl198 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Putative cytidylate kinase. | 0.929 |
Mfl528 | gmk | Mfl528 | Mfl195 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.914 |
Mfl528 | nrdI | Mfl528 | Mfl529 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleotide reductase; Probably involved in ribonucleotide reductase function. | 0.929 |
Mfl528 | tmk | Mfl528 | Mfl676 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.942 |
Mfl528 | trmFO2 | Mfl528 | Mfl532 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Glucose inhibited division protein C; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.413 |
NrdF | Mfl175 | Mfl530 | Mfl175 | Ribonucleoside-diphosphate reductase beta chain. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.913 |