node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rxyl_0639 | Rxyl_0640 | Rxyl_0639 | Rxyl_0640 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sco:SCO1853 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6409 putative methyltransferase. | 0.992 |
Rxyl_0639 | Rxyl_0642 | Rxyl_0639 | Rxyl_0642 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sco:SCO1853 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | KEGG: sma:SAV6408 precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; TIGRFAM: Precorrin-6y C5,15-methyltransferase, subunit CbiE; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.998 |
Rxyl_0639 | Rxyl_0643 | Rxyl_0639 | Rxyl_0643 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sco:SCO1853 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: sma:SAV6407 putative precorrin methylase. | 0.999 |
Rxyl_0639 | Rxyl_0645 | Rxyl_0639 | Rxyl_0645 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sco:SCO1853 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: sma:SAV6406 putative precorrin-8X methylmutase. | 0.991 |
Rxyl_0639 | Rxyl_0646 | Rxyl_0639 | Rxyl_0646 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sco:SCO1853 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: sma:SAV6405 putative metal binding protein. | 0.995 |
Rxyl_0639 | cbiD | Rxyl_0639 | Rxyl_0641 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sco:SCO1853 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.985 |
Rxyl_0639 | cobB | Rxyl_0639 | Rxyl_0638 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sco:SCO1853 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.972 |
Rxyl_0639 | cobD | Rxyl_0639 | Rxyl_0649 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sco:SCO1853 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.957 |
Rxyl_0639 | cobQ | Rxyl_0639 | Rxyl_0634 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sco:SCO1853 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.987 |
Rxyl_0639 | cobS | Rxyl_0639 | Rxyl_0648 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sco:SCO1853 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.944 |
Rxyl_0640 | Rxyl_0639 | Rxyl_0640 | Rxyl_0639 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6409 putative methyltransferase. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sco:SCO1853 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.992 |
Rxyl_0640 | Rxyl_0642 | Rxyl_0640 | Rxyl_0642 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6409 putative methyltransferase. | KEGG: sma:SAV6408 precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; TIGRFAM: Precorrin-6y C5,15-methyltransferase, subunit CbiE; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.999 |
Rxyl_0640 | Rxyl_0643 | Rxyl_0640 | Rxyl_0643 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6409 putative methyltransferase. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: sma:SAV6407 putative precorrin methylase. | 0.999 |
Rxyl_0640 | Rxyl_0645 | Rxyl_0640 | Rxyl_0645 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6409 putative methyltransferase. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: sma:SAV6406 putative precorrin-8X methylmutase. | 0.992 |
Rxyl_0640 | Rxyl_0646 | Rxyl_0640 | Rxyl_0646 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6409 putative methyltransferase. | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: sma:SAV6405 putative metal binding protein. | 0.929 |
Rxyl_0640 | cbiD | Rxyl_0640 | Rxyl_0641 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6409 putative methyltransferase. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.987 |
Rxyl_0640 | cobB | Rxyl_0640 | Rxyl_0638 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6409 putative methyltransferase. | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.976 |
Rxyl_0640 | cobD | Rxyl_0640 | Rxyl_0649 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6409 putative methyltransferase. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.960 |
Rxyl_0640 | cobQ | Rxyl_0640 | Rxyl_0634 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6409 putative methyltransferase. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.988 |
Rxyl_0640 | cobS | Rxyl_0640 | Rxyl_0648 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6409 putative methyltransferase. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.937 |