node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rxyl_0843 | Rxyl_1951 | Rxyl_0843 | Rxyl_1951 | PFAM: methylenetetrahydrofolate reductase homocysteine S-methyltransferase; KEGG: pca:Pcar_0238 methylenetetrahydrofolate reductase family protein. | PFAM: formyl transferase-like; KEGG: mlo:mlr1236 hypothetical protein. | 0.937 |
Rxyl_0843 | fhs1 | Rxyl_0843 | Rxyl_0766 | PFAM: methylenetetrahydrofolate reductase homocysteine S-methyltransferase; KEGG: pca:Pcar_0238 methylenetetrahydrofolate reductase family protein. | PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: pac:PPA0049 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.941 |
Rxyl_0843 | fhs2 | Rxyl_0843 | Rxyl_1568 | PFAM: methylenetetrahydrofolate reductase homocysteine S-methyltransferase; KEGG: pca:Pcar_0238 methylenetetrahydrofolate reductase family protein. | PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: pac:PPA0049 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.941 |
Rxyl_0843 | fhs3 | Rxyl_0843 | Rxyl_2519 | PFAM: methylenetetrahydrofolate reductase homocysteine S-methyltransferase; KEGG: pca:Pcar_0238 methylenetetrahydrofolate reductase family protein. | PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: pac:PPA0049 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.941 |
Rxyl_0843 | fmt | Rxyl_0843 | Rxyl_1467 | PFAM: methylenetetrahydrofolate reductase homocysteine S-methyltransferase; KEGG: pca:Pcar_0238 methylenetetrahydrofolate reductase family protein. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.937 |
Rxyl_0843 | folD1 | Rxyl_0843 | Rxyl_0827 | PFAM: methylenetetrahydrofolate reductase homocysteine S-methyltransferase; KEGG: pca:Pcar_0238 methylenetetrahydrofolate reductase family protein. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.938 |
Rxyl_0843 | glyA | Rxyl_0843 | Rxyl_0469 | PFAM: methylenetetrahydrofolate reductase homocysteine S-methyltransferase; KEGG: pca:Pcar_0238 methylenetetrahydrofolate reductase family protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.947 |
Rxyl_0843 | glyA-2 | Rxyl_0843 | Rxyl_1649 | PFAM: methylenetetrahydrofolate reductase homocysteine S-methyltransferase; KEGG: pca:Pcar_0238 methylenetetrahydrofolate reductase family protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.947 |
Rxyl_0843 | purH | Rxyl_0843 | Rxyl_1000 | PFAM: methylenetetrahydrofolate reductase homocysteine S-methyltransferase; KEGG: pca:Pcar_0238 methylenetetrahydrofolate reductase family protein. | KEGG: tfu:Tfu_2572 AICARFT/IMPCHase bienzyme; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme MGS-like. | 0.937 |
Rxyl_0843 | purN | Rxyl_0843 | Rxyl_0999 | PFAM: methylenetetrahydrofolate reductase homocysteine S-methyltransferase; KEGG: pca:Pcar_0238 methylenetetrahydrofolate reductase family protein. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.943 |
Rxyl_1951 | Rxyl_0843 | Rxyl_1951 | Rxyl_0843 | PFAM: formyl transferase-like; KEGG: mlo:mlr1236 hypothetical protein. | PFAM: methylenetetrahydrofolate reductase homocysteine S-methyltransferase; KEGG: pca:Pcar_0238 methylenetetrahydrofolate reductase family protein. | 0.937 |
Rxyl_1951 | fmt | Rxyl_1951 | Rxyl_1467 | PFAM: formyl transferase-like; KEGG: mlo:mlr1236 hypothetical protein. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.936 |
Rxyl_1951 | folD1 | Rxyl_1951 | Rxyl_0827 | PFAM: formyl transferase-like; KEGG: mlo:mlr1236 hypothetical protein. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.947 |
Rxyl_1951 | glyA | Rxyl_1951 | Rxyl_0469 | PFAM: formyl transferase-like; KEGG: mlo:mlr1236 hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
Rxyl_1951 | glyA-2 | Rxyl_1951 | Rxyl_1649 | PFAM: formyl transferase-like; KEGG: mlo:mlr1236 hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
Rxyl_1951 | purN | Rxyl_1951 | Rxyl_0999 | PFAM: formyl transferase-like; KEGG: mlo:mlr1236 hypothetical protein. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.925 |
fhs1 | Rxyl_0843 | Rxyl_0766 | Rxyl_0843 | PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: pac:PPA0049 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | PFAM: methylenetetrahydrofolate reductase homocysteine S-methyltransferase; KEGG: pca:Pcar_0238 methylenetetrahydrofolate reductase family protein. | 0.941 |
fhs1 | fhs2 | Rxyl_0766 | Rxyl_1568 | PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: pac:PPA0049 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: pac:PPA0049 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.900 |
fhs1 | fhs3 | Rxyl_0766 | Rxyl_2519 | PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: pac:PPA0049 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: pac:PPA0049 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.900 |
fhs1 | folD1 | Rxyl_0766 | Rxyl_0827 | PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: pac:PPA0049 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.991 |